Laboratory Products 43 Engineered Knockout Cell Lysates for Reproducible Proteomic Analysis
Abcam’s new engineered knockout cell lysates enable proteomic studies by providing researchers with ‘true negative’ controls. Acquiring reliable off-the-shelf knockout mouse models or cell lines that match specific experimental requirements can be challenging, and often need to be sourced directly from individual researchers or labs. Abcam’s newly-launched collection addresses this issue by providing access to over 2,800 diploid KO cell lysates, the largest selection currently available to researchers.
The lysates are useful for studies requiring loss-of-function phenotypes at the proteomic level as well as routine applications such as Western blotting and mass spectroscopy. They also can be used to support antibody and target validation. The use of diploid cells makes the lysates well suited to the more complex studies often carried out in cancer research. Derived from commonly used immortalised cell lines, KO lysates have been engineered using CRISPR-Cas9 and are accompanied by Sanger sequencing and Western blotting validation data. Corresponding wild-type controls are also provided so that the biological impact of each KO lysate can easily be assessed within a consistent cellular background.
Abcam’s KO cell lysates deliver: access to thousands of CRISPR-Cas9-engineered KO cell lysates of interest, without needing to generate or purchase a KO cell line, saving on average 4–12 weeks’ work in the lab; minimal preparation required; Diploid KO lysates derived from commonly used cell lines including HeLa, HEK293T, A549, HCT116, Hep G2 and MCF.
More information online:
ilmt.co/PL/V1yd 50846pr@reply-direct.com
Healthier Air in the Lab
Exposure to unwanted chemical emissions are an unfortunate reality when working in a lab. Even if you can’t smell them, Erlab’s Halo laboratory- grade molecular air filtration system can.
Halo is working 24/7 to clean the air in the lab. Once vapours are detected, Halo will capture them in Erlab’s proprietary carbon filtration technology. After adsorbing the molecules that cause unwanted odours, clean air is returned back to the room through low-disruptive side vents.
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Fine Mesh Baskets for Washing/ Sterilising Very Small Parts
WPI has introduced a series of Micro Fine Mesh Baskets which are ideal for washing or sterilising very small parts.
The series of baskets consists of many sizes from 40 x 40 x 20 mm up to 180 x 130 x 20 mm. The Micro Fine baskets are constructed with micro fine mesh with opening squares of 1.0 mm and wire diameter of 0.5 mm.
In addition to the Micro Fine Baskets, WPI also offers a series of Fine Mesh Baskets and a series of Perforated Baskets. The basket selected would be determined by the parts being cleaned or sterilised.
These baskets are manufactured with 304 stainless steel that has been electrolyte polished. Each basket is provided with a lid with a wire locking clip.
51296pr@reply-direct.com ADVERTORIAL Cooled Incubators Series 3
The LMS Series Three Cooled Incubator is a reliable and accurate temperature controlled cabinet (-10°C to +50°C) which has proved its worth over many years in laboratories both in the U.K. and overseas.
The design of the purpose built incubator facilities the addition of optional extras to provide greater flexibility for individual use, making it suitable for a wide range of applications including:-
The study of growth patterns of plants and insects, B.O.D. Tests, Seed germination & vernalisation, Tissue culture, Enzyme testing, Serum studies, Immunology, Fruit fly culture, Sample storage, Product shelf life tests.
We can Now Offer a Bespoke Range of Cabinets for you to choose the Size, Volume, Layout, Specification and Material Finish
7546pr@reply-direct.com Series 1A Cooled Incubators
The LMS Series ‘1A’ Cooled Incubator is a reliable and accurate Temperature controlled cabinet (-10°C to +50°C) designed for optimum performance and reliability.
The design of the purpose built incubator facilitates the addition of optional extras to provide greater flexibility for individual use, making it suitable for a wide range of applications.
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Specialists in a Bespoke and Standard Range of Temperature Contolled Incubation Cabinets LMS have been assisting the laboratory world for over 45
years, principally manufacturing cooled incubators and the service, repair and UKAS calibration of laboratory equipment.
Whilst we continue to develop and upgrade our existing ranges of cooled incubators and offering a range of optional extras to suit your particular needs. We can now offer a bespoke range of cabinets for you to choose the size, volume, layout, specification and material finish.
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LMS.indd 1 24/10/2019 10:40 -10˚C +50˚C
Specialist in
Cooled Incubation From 72 litres to 1200 litres
WWW.LABMATE-ONLINE.COM
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