41 The Latest in Freeze Dryers for R&D Labs
Telstar will be unveiling ‘LyoQuest’, the latest in its line of laboratory freeze dryers, which has a condensation capacity of 8 litres and can carry out pre-freezing, primary drying, and secondary drying processes. This new innovation is the only bench-top laboratory freeze dryer on the market that combines this breadth of functionality into a single unit so that users can perform complete cycles on a range of sample containers (vials, trays, ampoules, and flasks) using the same piece of equipment.
In addition to being versatile, LyoQuest also allows users to create recipes comprising time, temperature and vacuum control thanks to its integrated PLC control system. This easy-to-use device includes a touch-screen HMI with an intuitive menu and mimic diagram. The ‘LyoLogger’ monitoring software enables connection of the unit to a PC so collected data can be transferred to files for analysis using Microsoft Excel. The software also makes it possible to view graphs showing the pressure, condenser temperature, and, if working with a chamber, product and tray temperature as well. The innovative design of this freeze dryer results in an extremely compact unit with large condensation capacity. The LyoQuest’s ice condenser is made from AISI 316L stainless steel and includes an automatic defrosting function for quick and easy deicing. Furthermore, its design enables many product formats to be pre-frozen by the device, without the need for an additional freezer.
This LyoQuest freeze dryer is specially designed for labs in research and development departments of universities, hospitals, scientific institutes, biotechnology centres, pharmaceutical companies, and food companies.
Circle no. 159
Improve 3- Dimensional Cell Culture with Iwaki Vecell from Sterilin
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New Iwaki Vecell 3-dimensional cell culture inserts, available from Sterilin, provide improved cultivation of adherent cell cultures and reliable cell growth. The inserts are designed for use with either 6 or 24 well culture plates.
In the past century, cell culture has become a widely used technique in research laboratories, starting with vaccine development in the early 1900’s. The more advanced techniques used today give scientists a better understanding of cellular processes and, in particular, the effects of disease. In order to proliferate, adherent cell lines need a surface on to which they can anchor. When grown using traditional plastic surfaces, the cultured cells form strong interactions with the Tissue Culture (TC) surface and the technician is then required to ‘spread’ the cells – leading to unnatural flattening of the cell nuclei.
Because there is no requirement for spreading cells across the TC growth surface, the Vecell 3- Dimensional scaffold promotes cell adhesion and proliferation without causing cell stress. The Vecell membrane is porous, enabling both cells and medium to easily pass through, mimicking in vivo tissue. This encourages cell-cell interactions and metabolic activities to occur as they would in their natural environment. Additionally, the uniformly thin layered membrane has a collagen coated surface to aid cell attachment and promote cell growth. Further modification is not required before seeding cells. Cells cultured using a Vecell insert can be viewed using Phase Contrast Microscopy and the membrane can also be easily prepared for use with both Scanning and Transmission Electron Microscopes.
Vecell inserts are sterilised using ethylene oxide gas and are supplied in individual blister packs with pack quantities of 12 (for 6 well plates) or 24 (for 24 well plates) with a 2-year shelf life from the date of manufacture.
Circle no. 160
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