Mass Spectrometry Focus
New Vials Let Users Anticipate Unexpected Peaks
Agilent Technologies Inc introduced Agilent MS Analysed Vials, the first vials and closures to have been analysed by GC/MS and LC/MS and shipped with their mass spectra in a single package. The new vials allow scientists to anticipate any ghost peaks caused by the vials, thereby eliminating unnecessary rework. The vials, caps and septa, and their analytical data are lot-specific and fully traceable.
“The rapid adoption of extremely sensitive mass spec systems puts more emphasis on the need for high-purity, validated supplies,” said JR Daversa, Agilent Global Marketing Program Manager, Chemistries and Supplies Division. “By analysing these vials and closures and including lot-specific MS data, we’re saving users the effort of performing this step while still achieving high-confidence results.”
In addition to the vials and certificate of analysis, each kit contains septa and caps for convenience. They are available in certified screwtop and crimp- top vial packs, in clear or amber glass. Users can choose virtually any combination of certified vials, caps and septa for their applications.
Circle no. 56 Economic Solution for Routine Tasks
Shimadzu has introduced the new GCMS-QP2010 SE, completing the new quadrupole series together with the GCMS-QP2010 Ultra. A variation of the Ultra model, the SE version focusses on high productivity features with an exceptionally good price/performance ratio. This makes it an ideal tool for routine analysis in laboratories covering different application areas, such as environmental analysis or quality control. A multitude of accessories supports the flexible use of the GCMS-QP2010 SE. These either extend the variety of applications or help to streamline processes in order to save time: the optional Direct Inlet allows analysis of compounds with lower volatility; for analysis of compounds of even higher molecular mass (e.g. polymers, paints, woods and resins) an optional pyrolyzer system is available (Py-2020, Frontier lab); the TD-20 thermal desorption system specialises in working with very volatile compounds; the AOC-20 autosampler enables programming of a two-step derivatization method eliminating the need for a tedious derivatization process in the lab, e.g. for clinical applications; the temperature programmable Optic 3 injector (Atas GL) with its rapid heating characteristic is the choice for applications in flavor and fragrance analysis; using a ‘double jet cooling system’ the GC-2010 Plus oven in the GCMS-QP2010 SE is cooled down rapidly, for example, in 2.7 minutes from 350°C to 50°C. This significantly reduces analysis time, particularly in applications analysyng VOCs (volatile organic compounds); and the Shimadzu Easy sTop Quick changer system even changes septum and liner without breaking the vacuum, thereby saving valuable time.
Circle no. 58 ADVERTORIAL The Pegasus® 4D GCxGC-TOFMS
Leco's Pegasus 4D GCxGC-TOFMS gives you four dimensions of analytical resolution for a significantly more complete analysis of complex samples. The Pegasus 4D combines unparalleled chromatographic resolution with incredible acquisition rates (500 spectra/sec) and industry leading spectral deconvolution.
ChromaTOF® software now features peak labeling for both contour and surface GCxGC plots, graphing capabilities as well as several user interface improvements to improve the analysts speed & efficiency.
Leco’s Statistical Compare Package and Leco/Fiehn Metabolomics Library work seamlessly with the Pegasus 4D to perform peak alignment, allow for the classification of analytes and identify trends in sample groups.
Circle no. 59 New ChromaTOF® Software Version Now Available
Leco Corporation is pleased to announce the release of ChromaTOF version 4.30, the exclusive operating software for its Separation Science instrumentation. In addition to the same renowned functionality and time-saving features of previous software versions, ChromaTOF 4.30 offers an improved user interface, the option of defining user permissions, and the ability to perform variable modulation. With variable modulation, users can modify modulation settings within each chromatographic run for a more specialised analysis, maximising resolution in both the first and second dimensions. ChromaTOF 4.30 is included with any new Leco Pegasus®
HT GCMS or
4D GCxGC-MS, TruTOF® HT GCMS, or GCxGC instrument. Upgrades for existing versions are also available. For more information, visit
www.leco.com.
Circle no. 60 The TruTOF® HT GC-TOFMS
The TruTOF offers continuous full- range mass acquisition rates up to 80 spectra/second for accurate identification of unknown and targeted compounds in complex samples. A unique benchtop design delivers all of the high-throughput benefits of GC-TOF in a space-saving package. Exclusive ChromaTOF®
4.30 software with True Signal Deconvolution® Circle no. 61
IC-MS Technique for Metabolomics Studies
Dionex is pleased to announce the release of a Customer Application Note (CAN) demonstrating the use of ion-exchange chromatography coupled with mass spectrometry for the separation for polar compounds present in biological samples. CAN 108: Ion Chromatography Coupled with Mass Spectrometry for Metabolomics demonstrates efficient separation of biological metabolites using ion chromatography with MS detection. Ionic and polar compounds such as organic acids, carbohydrates, nucleotides, and amino acids are difficult to separate using traditional reversed-phase columns. The technique presented in CAN 108 demonstrates effective separation of these compounds using ion-exchange followed by on-line desalting to allow mass spectrometric detection. By combining the best features of both techniques, this method provides ultralow levels of quantitation in a wide variety of biological matrices, including blood, urine, and sera.
Circle no. 55
High-Resolution Mass Spectrometer Product Update
The AB SCIEX TripleTOF™ 5600 System is the life science industry's fastest and most sensitive high-resolution mass spectrometer for high-performance qualitative and quantitative analysis. This system combines for the first time on a single platform the quantitative capabilities typically associated with triple quadrupoles and the qualitative capabilities of a high- resolution accurate-mass system. The TripleTOF 5600 System provides access to powerful new workflows for comprehensive exploration, rapid profiling and high-resolution quantitation of complex samples. It delivers a series of new innovations, including SmartSpeed™ 100Hz Acquisition, which gives 5 times higher speed than any other high-resolution mass spectrometry system; Accelerator TOF™ Analyser for rapid high-resolution data with the industry’s highest sensitivity; and EasyMass™ Accuracy to achieve stable ~1ppm mass accuracy without continuous user calibration.
Circle no. 57
provides fast and easy data
analysis and clean library searches. The TruTOF also includes environmental reporting software, and offers both electron and chemical ionisation sources for increased laboratory productivity.
Circle no. 62
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