MICROSCOPY&MICROTECNIQUES NEWS 75
BHT Offers Potential for Early Cancer Detection
As the potential cancer population increases, an effective long-term solution for early cancer detection needs to be found. In some areas of the world, cancer incidence is growing by 3% per annum, and the cost of cancer care is a ticking time bomb for global healthcare expenditure. According to latest research from Frost & Sullivan, a novel approach to cancer diagnostics is on the rise, capable of targeting a specific organ or region of interest and enabling refined and high-resolution image capture and analysis. Bioholo-tomography (BHT) is a technology which acquires holographic information for diagnostic purposes on any affected region of the body using only surface readings.
This low-cost imaging technique does not require any exposure to ionising radiation and is the technology behind a device called the Cancer Instant Detector (CID) developed by Advanced Bioresearch & Technology Ltd (ABR), together with the Center of Bioholography Ltd, Georgia. Detection of cancer at its earliest possible stages remains the best strategy for improving cancer patients’ quality of life and reducing cancer deaths. Yet the majority of cancers in early development stages have no obvious symptoms and may not be detected unless an individual arrives for a routine check-up at the physician office or as part of cancer screening programmes. “The CID incorporates a simplified and portable device that can rapidly capture diagnostic-quality information capable of revealing both physiological anomalies,” explained Research Analyst Prasanna Vadhana Kannan from Frost & Sullivan’s Technical Insights Group, who have been tracking the developments of the technology since 2005. “Through CID, a full-body scan is accomplished by non- invasive examination of the induced emissions from the fingertips.” Using the CID as a detection tool, the probability of cancer, its location within a pre-defined body segment and the degree of aggressiveness can be determined and displayed within seconds.
“The entire non-invasive procedure with a CID lasts only a few minutes and is harmless for patients, operators and the environment,” said Dr Marina Shaduri, founder of the Center of Bioholography in Tbilisi, Georgia.
“Any doctor would benefit from this new option of diagnostics, since the CID would detect cancer at early stages in a user-friendly way and it would also determine its location in a defined body segment body as well as the aggressiveness of pathology,” she added.
“By using the CID in association with established imaging modalities, unnecessary biopsies and surgery could be avoided. Such a modality might be used for both the detection of cancer and the monitoring of a patient’s condition in order to evaluate the efficiency of any therapeutic procedure or drug,” concluded analyst Prasanna Kannan.
For further information on Bioholo-tomography, the CID or investment opportunities in Advanced Bioresearch & Technology Ltd, please contact Katja Feick at
katja.feick@frost.com.
Circle no. 188 Circle no. 189
A 49 µm x 49 µm STEM-in-SEM image of rat hippocampus acquired on a Zeiss Supra 40 equipped with ATLAS™ (left) at 2nm per pixel. The inset square covers a region of approximately 9 µm x 9 µm (right).
Courtesy of: John Mendenhall, Center for Learning and Memory, University of Texas at Austin.
Carl Zeiss has launched ATLAS™, a powerful hard- and software package, which, can be combined with any CZ scanning electron microscope from Carl Zeiss for imaging of large-area specimens with nanometer resolution.
The system is initially being utilised both in the area of neurological research, e.g. the young field of brain mapping, and for traditional routine tasks in histology and pathology as a cost-effective method of examining specimens with constantly increasing sizes using resolutions in the nanometer range.
With suitable specimens, unattended operation can acquire multi-image montages that span extremely large fields of view, permitting capture of regions on the millimeter scale with resolution on the nanometer scale in a handful of hours. The in-built viewer software with integrated zoom function facilitates continous enlargement of the final image from rough overview until nanometer resolution, the company said.
Nanoscopic Analysis of Large-area Samples
Diary Date: Inter/Micro - 12/07/2010 Chicago USA Inter/Micro 2010 celebrates its 62nd
anniversary! The McCrone Research Institute celebrates its 50th
anniversary and its 50th
conference. This year the international microscopy symposium will be held entirely at the McCrone Research Institute. Inter/Micro 2010 celebrates the 62nd
anniversary of hosting the Anniversary of these microscopy conferences founded by Walter C. McCrone and Charles Tufts, and first held in
Chicago in 1948. Over the years, Inter/Micro has grown to attract microscopists, both amateur and professional, from all areas of light and electron microscopy. These symposia are held every year in Chicago and McCrone Research Institute celebrates its 50th the conference. Special workshops are to be announced and speakers include Dr Brian J. Ford, Skip Palenik.
anniversary and its 50th anniversary of hosting
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