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the cell membrane (Figure 2). Due to the change of the cell membrane structure and fluidity, the receptors and enzymes needed to import key nutrients are impaired. Next to in- creased cell permeability and the inhibition of enzymes, me- dium chain functional lipids can disrupt the electron trans- port chain in the cellular membrane. They directly bind to the transport carriers and changing the structure via increased membrane fluidity resulting in less energy for the cell. Other proposed mode of actions for medium chain functional lipids are lowering the pH inside and outside the cell, decreasing pathogen toxin production, interfering with pathogen adhesion and disrupting cell to cell signalling.


Functional lipids in practice In a trial carried out at Pipestone in the USA in 2019, Lipo- Vital reduced PRRS virus in the feed by 67%. It re- duced clinical disease compared to the control group and successfully controlled viral infections. The test also re- vealed that the growth rate was 2.5 times higher than in the control group. A performance trial carried out at the University at Rostock, Germany in 2019 focused on the performance and health parameters in broiler feeding with an additional clostridia challenge. The results showed improved performance (higher daily gain/im- proved FCR) in the broilers. LipoVital also had an influence on fatty liver syndrome and significantly reduced C. perfringens in the bird. There was an improvement on the growth performance in nursery pigs with Streptococcus suis is-


sues. LipoVital reduced mortality rates and improved the feed conversion rate, which in turn resulted in a higher in- come for the farm. This trial was conducted in cooperation with a German feed producer. At the Kaseart University of Bangkok, LipoVital was used in white shrimp in a trial where the focus was on growth, survival, immune response and intestinal bacteria composition. The study showed there was a significant increase in immune functions and performance as well as a reduction in mortality rates. Medium chain functional lipids show promising results and contribute to a stable gut health and therefore to more robust animals.


References and additional information available on request Figure 2 - Cell membrane structure. Lipoteichoic acid Teichoic acid Peptidoglycan


Cytoplasmic membrane


Porin Membrane protein Phospholipid ▶ GUT HEALTH | DECEMBER 2020 85


Medium Chain Functional lipids have a positive influence on gut health.


PHOTO: ISTOCK


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