Added value of esterified organic acids
The financial success of animal rearing is directly related to gut health. To avoid performance losses, it is of utmost importance for farmers and veterinarians to closely monitor the development of the gut mucosa and associated microbiota.
BY DR JULIE FEYAERTS, PRODUCT DEVELOPMENT MANAGER, PROVIRON T
The added value of esterification of SCFA’s and MCFA’s.
Butyric acid Non-esterified
Esterified place of action Esterification impact:
• Optimized delivery • pH independency • Gradual enzymatic release along the entire gut
he intestine is the most predominant gate between expensive feed input and qualitative production out- put. The huge surface area of the intestinal mucosa is constantly in direct contact with the luminal content.
This mucosal barrier is providing an adequate protection against the invasion of pathogenic bacteria, viruses and toxins, but is also assuring an optimal absorption of nutrients. Fulfill- ing both functions simultaneously requires a well-balanced -rich and diversified- microbiome composition, specifically
Place of action
located along the intestinal tract. Any factor compromising the intestinal mucosa’s integrity and microbial balance will affect animal health and performance in commercial operations.
Organic acids Organic acids are widely present in nature. They occur in plants, animals and humans, and are produced by intestinal bacterial fermentation of fibres, starches and sugar. Organic acids are called Short Chain Fatty Acids (SCFA) when containing less than 6 carbon atoms, and Mid Chain Fatty Acids (MCFA) when containing 6 to 14 carbon atoms. Some organic acids have a long history of use as preservative. The antimicrobial action of organic acids as preservative in feed or drinking water occurs through lowering the pH, reducing the feeds buffering capacity and affecting the microbial population in feed or water. More important, however, is the fact that organic acids can also have beneficial effects inside an animal’s digestive tract by steering the complex
Mode of action Multi-targeted approach to support gut health
Antiviral Antibacterial
MCFA’s Non-esterified Tight Esterified place of action Nutrients Esterification impact:
• Optimized delivery • Highly antimicrobial • Extended field of activity along the entire gut
Enzymes
Absorption of nutrients
Digestion
Digestive enzyme secretions
LAMINA PROPRIA Immune system junctions Villi length Gut
barrier function
Beneficial microflora
Microflora balancing
Pathogens
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▶ GUT HEALTH | DECEMBER 2020
Effectiveness
PROVIRON, BELGIUM, 2020
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