EVALUATING THE IMPACT OF TWO IONOPHORE+NICARBAZIN COCCIDIOSTATS ON INTESTINAL INTEGRITY & PERFORMANCE
Coccidiosis costs global poultry producers more than $4 billion in losses every year.1
Poor Intestinal Integrity caused by
coccidiosis can increase FCR by as much as 0.1 and also negatively impact mortality and body weight.2,3
as high as 0,04€/bird or higher.4
producers can take proactive steps to protect Intestinal Integrity, improve feed effi ciencies and increase weight gains.
Protecting Intestinal Integrity: anticoccidials
Many anticoccidial molecules have been introduced to the global poultry industry as feed additives. Chemical anticoccidials work well for severe challenges, but longer term usage can result in increased resistance. On the other hand, ionophores effectively prevent coccidiosis while also allowing natural immunity to develop.1
About the study: materials and method1
A recent study compared the effectiveness of two ionophores—Monensin and Narasin—in combination with Nicarbazin to control coccidiosis and sought to establish how these two anticoccidials differ in their infl uence on bird performance and gut health.
The trial examined 4,400 Ross broilers challenged with coccidia and evaluated them based on growth performance and the presence of macroscopic lesions on internal organs.
Birds received feed supplemented with either Monensin + Nicarbazin (MN) or Narasin + Nicarbazin (NN) for days 0 to 27, followed by use of Narasin until market weight.
Twenty-fi ve percent of birds in each pen were randomly weighed individually at 27 and 33 days of age. Feed intake per fl oor pen at day 27 and at the end of the study (day 33) were recorded and feed conversion values were computed. Lesion scoring was performed on 66 birds per treatment diet (3 birds/pen).
Results: Intestinal Integrity1
Proportion of birds where coccidiosis gross lesions were observed was reduced by both treatments, Monensin + Nicarbazin and Narasin + Nicarbazin, recording no signifi cant differences.
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Score
Combined costs can be However,
COCCIDIOSIS LESION SCORES* OF BROILERS FED NN OR MN AT 22 D
Monensin + Nicarbazin
Gross Eimeria acervulina (gAC) 066
Gross Eimeria maxima (gMx) 055
Gross Eimeria tenella (gTN) 057
* Scores: 0 = absent, 1 = slight, 2 = severe (n = 66 birds/treatment)
FCR and live BW1
The group treated with Narasin + Nicarbazin demonstrated a signifi cantly lower feed conversion ratio and signifi cantly increased live body weight at days 27 and 33 as compared to the group treated with Monensin + Nicarbazin.
PERFORMANCE OF BROILERS FED NN OR MN AT 27 D Parameter
Monensin + Nicarbazin
Feed conversion ratio
Live body weight (g) a,b
1.566a 1284a
1.458b 1405b
Values with different superscripts are signifi cantly different (P<0.05). n = 550 birds/treatment
PERFORMANCE OF BROILERS FED NN OR MN AT 33 D Parameter
Monensin + Nicarbazin
Cumulative Feed Conversion
Live body weight (g) a,b Carcass quality1
Ready-to-cook weight was signifi cantly improved in the group treated with Narasin + Nicarbazin as compared with the group treated with Monensin + Nicarbazin. Also, the breast weight was signifi cantly improved in the group treated by Narasin + Nicarbazin as compared to the group treated with Monensin + Nicarbazin.
CARCASS YIELD OF BROILERS FED NN OR MN UNTIL 27 D FOLLOWED BY NARASIN UNTIL 33 D
Parameter Live weight (g)
Ready-to-cook (g) Breast weight (g)
a,b
Monensin + Nicarbazin
2032b 1400a 580b
Narasin + Nicarbazin
2159a 1517b 656a
Values with different superscripts are signifi cantly different (P<0.05). n = 110 birds/treatment
1.642a 2026a
1.549b 2178b
Values with different superscripts are signifi cantly different (P<0.05). n = 550 birds/treatment
References: 1
Narasin + Nicarbazin
2 3
Farran MT, Shahib H, Hakeem WG, Kaouk ZM, Harkous AA. Performance of Eimeria challenged male broilers fed two ionophore-Nicarbazin combination. Journal of Applied Poultry Research. 2020; 29:684–691.
Williams R. A compartmentalized model for the estimation of the cost of coccidiosis to the world’s chicken production industry. Int. Journ. for Parasitology. 1999; 29(8).
Brennan J, Bagg R, Barnum D, Wilson J, Dick P. Effi cacy of Narasin in the Prevention of Necrotic Enteritis in Broiler Chickens. Avian Diseases. 2001; 45:210.
4
van der Sluis W. Clostridial enteritis is an often underestimated problem. World Poultry. 2000; 16(7).
Narasin + Nicarbazin
Narasin + Nicarbazin
66 55
18 10 23 1
56 19 10
Key points: Ionophore- Nicarbazin Combinations
Narasin + Nicarbazin signifi cantly improved the performance parameters of Ross 308 broilers challenged with coccidia, namely live body weight at market age and cumulative feed conversion in comparison to Monensin + Nicarbazin.1
Narasin + Nicarbazin improved the carcass quality in comparison to Monensin + Nicarbazin. Ready-to- cook carcass and other carcass parts were signifi cantly improved by Narasin + Nicarbazin in terms of weight and weight percentages.1
When selecting a coccidiostat, Narasin + Nicarbazin is considered a signifi cantly better choice with a greater value to the broiler producer in comparison to MN.1
INTESTINAL INTEGRITY (I2 CORNER
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