ANTI-AGEING Volume of wrinkles 0 –5
–10 –15 –20 –25 –30
Area of wrinkles 0
–2 –4 –6 –8
–10 –12 –14 –16 –18 –20
Nasal furrows Forehead lines Circumoral wrinkles
Figure 7: Effect of Matrigenics.14 G on the volume and area of forehead lines, circumoral wrinkles and nasal furrows a) after 14 days and b) after 28 days.
In vivo evaluation of the anti-ageing effect of the Undaria pinnatifida extract The anti-ageing effect of the Undaria pinnatifida extract was measured using a new fringes projection technology named Face Scanner III-EO, recently developed by the company Eotech (Marcoussis, France). This technology uses the technique of fringes projection with 180˚ configuration. The machine can assess the signs of facial ageing in 3D. The Undaria pinnatifida extract was
tested at 2% in a cream against a placebo, by two panels of 22 volunteers, applying the product twice a day. The effect of the Undaria pinnatifida extract on forehead lines, nasal furrows and circumoral
a
wrinkles was evaluated after 14 and 28 days of treatment. Average results are presented in Figure 7, with data expressed versus placebo.
Effect on the forehead lines After 14 days of application the Undaria pinnatifida extract significantly reduces the volume (–23.8%) and the area (–14.4%) of forehead lines (Fig. 8). It reduces them by 17% and 12% after 28 days.
Effect on the nasal furrows The volume and area of nasal furrows are reduced by 2% and 6% respectively after 14 days and by 8% and 9% after 28 days (Fig. 9).
b
Effect on the circumoral wrinkles The Undaria pinnatifida extract reduces the volume and area of circumoral wrinkles by 3% and 4% after 14 days and by 18% and 16% after 28 days.
Conclusion Thanks to its richness in Wakamic ester, Matrigenics.14 G activates 14 genes involved in the synthesis of the main components of extra cellular matrix: collagen, elastin and hyaluronic acid. In only 14 days Matrigenics.14 G restructures the dermis and reduces wrinkles volume and area, thus acting against inversion of the triangle of beauty and the accentuation of negative expressions.
Volume of wrinkles Area of wrinkles
PC
Figure 8: View of the effect of Matrigenics.14 G on forehead wrinkles and forehead lines of a volunteer a) before treatment and b) after 28 days. a b
Figure 9: View of the effect of Matrigenics.14 G on nasal furrows and circumoral wrinkles of a volunteer a) before treatment and b) after 28 days. March 2012 PERSONAL CARE 43
Average variation vs. placebo (%)
Average variation vs. placebo (%)
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