Proteomics, Genomics & Microarrays
New Horizontal and Vertical Gel Electrophoresis Equipment Produces Perfect Gels
Syngene is delighted to announce the launch of a new range of robust horizontal and vertical gel electrophoresis equipment. The new units save scientists time and effort by providing an easy to use, versatile platform to run consistent quality DNA and protein gels for visualisation in Syngene’s imaging systems.
With a wide range of tank and tray sizes, as well as many comb options, the new Syngene horizontal and vertical electrophoresis units can run a huge variety of PAGE and agarose gel types and sizes, all of which are compatible with visualisation in Syngene imaging systems. Featuring sturdy injection moulded construction and corrosion-resistant platinum electrodes, all the tanks in the range offer a robust, leak proof-environment, guaranteeing user safety and long product life.
In a choice of four sizes, the horizontal gel units, known as the SynMini, SynMidi, SynChoice and SynMaxi allow scientists to run gels as small as 7cm x 7cm right up to 20cm x 20cm. Each tank comes with two or three (for the SynChoice) sizes of cleverly designed indentation free, UV transparent gel trays and a choice of combs in four different thicknesses. These combined features make the new Syngene horizontal gel electrophoresis units the most cost-effective and versatile solution for running DNA and RNA gels currently available.
With a choice of two sizes, Syngene’s SynPAGE and SynWave vertical electrophoresis tanks can be used with 10cm x 10cm or 20cm x 20cm gels to run up to four hand cast (additional plates required) or two commercial pre-cast gels from any major supplier. Featuring glass plates with permanently bonded spacers that are easy to seal between pressure bars, guarantees consistent gel thickness and leak free casting. For cost-effective versatility, scientists wanting to transfer their proteins to Western blots, can also fit the new Syngene vertical electrophoresis tanks with a modular blotting insert.
“Scientists using Syngene’s G:BOX and NuGenius systems often ask us to recommend the best gel electrophoresis equipment to use with them,” says Dr Martin Biggs, Divisional Manager at Syngene. “We’re delighted to fill that gap in their workflow by offering a range of versatile, high-quality horizontal and vertical electrophoresis equipment to help them easily cast, run and then rapidly visualise their gels with Syngene imaging systems.”
More information online:
ilmt.co/PL/aDYr 49369pr@reply-direct.com
First Commercially Available Venezuela Equine Encephalitis Virus (VEEV) Protein Announced
On the occasion of the 11th International Global Virus Network meeting, Aalto Bio Reagents launches the first commercially available protein for the detection and diagnosis of Venezuela Equine Encephalitis NSP2 TC83.
Venezuela Equine Encephalitis is a mosquito-borne viral pathogen that causes Venezuela Equine Encephalitis or Encephalomyelitis (VEE). VEE can affect humans and animals alike causing flu-like symptoms and headaches in healthy humans and causing serious illness and death in the young, the elderly, and immunocompromised patients.
“This exciting VEEV NSP2 TC83 launch today marks the first in a series of dynamic new products coming from Aalto Bio in the emerging disease space,” said Philip Noone, CEO, Aalto Bio. “With this new VEEV NSP2 TC83 protein it enables our customers to bring superior, differentiating diagnostic end-products to market faster which will enable faster diagnosis, identification and treatment of these deadly viruses.”
The virus that causes VEE can be spread mainly by mosquitos that bite and infect humans and or animals. The virus can spread very quickly dependent on the subtype of VEE that is transmitted and the density of the mosquito populations near an outbreak region. Enzoonotic subtypes of VEE are endemic to certain geographical areas.
There is an inactivated vaccine available for animals which contains the C-84 strain for VEEV, and it is primarily used on horses. In the case of humans there is another rudimentary vaccine which contains the TC-83 strain and is only used to date on military and lab personnel. However, clinicians have found that the vaccine does have side effects and does not fully immunize the patient. The team at Aalto Bio believe their new protein will help further the development of a more mainstream vaccine which will give greater or full immunisation to vaccine candidates and allow faster infield diagnostics of the virus. It should also be noted that during the cold war, both the US and Soviet biological weapons program researched and developed the VEEV virus.
“Aalto Bio are a leading global developer and provider of high-quality and esoteric biological raw materials to the in-vitro diagnostic and Biotech industry,” stated Jennie Lynch, Senior VP North America, Enterprise Ireland. “We are glad to support them in bringing ground-breaking technology to the frontier of Biotechnology and Pharmaceuticals.”
49477pr@reply-direct.com
Solution for NGS Library-construction in Cases of Small Samples and Limited Lab Space
Until now, the automated construction of Next Generation Sequencing libraries has only been economical for preparations of at least 96 samples, as entire plates are processed using multichannel dispensing tools. Furthermore, large pipetting stations are often costly and take up valuable space in the laboratory. As a result, smaller sample numbers are processed manually using pipettes. This approach requires time and concentration, and it involves a multitude of pipetting steps. Pipetting errors are difficult to avoid entirely, and they are rarely traceable. At the same time, NGS libraries, and the quality of their sequences, rely on the accuracy and reproducibility afforded by automated pipetting stations.
A solution is now available for all researchers who work with small sample numbers, whose laboratory space is limited or who generate NGS libraries manually. Up to 24 samples can be processed simultaneously in a fully automated fashion using the epMotion® 5073m NGS solution. The work station is optimised in such a way that almost no intervention is required and the construction of the library can proceed independently. Smooth operation is guaranteed by ample space for a sufficient number of pipette tips, the three required single and multichannel pipetting tools in the volume range covering 5-300 µL, and a special rack that accommodates all the required solutions.
The renowned precision and accuracy of Eppendorf pipettes also applies to the dispensing tools within the epMotion. The optimised epBlue™ software enables smart use of the single channel and multichannel dispensing tools in order to optimise pipetting steps and tip use even in the case of odd sample numbers. This saves time and money, and it reduces waste. And all of that on a footprint of only 6 letter-sized pieces of paper. Notification emails generated by the system to alert the user about manual steps allow the operator to step away from the instrument and focus their attention on other tasks.
The connection to VisioNize® enables monitoring of run time, mixer temperature and instrument status of the PC as well as mobile terminal devices. The solution for the construction of your NGS library: epMotion® 5073m NGS solution. More information online:
ilmt.co/PL/xemM
49186pr@reply-direct.com
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