The Bioanalysis Glossary


• 146 hematocrit The volumetric proportion of red blood cells in whole blood.


• 147 hemolysis


Lysis (rupture) of red blood cells resulting in release of hemoglobin and other cellular matter into the plasma and thus changing its composition.


• 148 hepatic clearance


The hypothetical volume of distribution in milliliters of unchanged drug cleared in 1 min via the liver.


• 149 high-performance (or pressure) liquid chromatography (HPLC)


Chromatographic technique where the sample is injected onto a liquid mobile phase, which is pumped at high pressure through a column, packed with adsorbent material (stationary phase). Often more simply referred to as LC.


• 150 high-resolution mass spectrometry (HR-MS)


Mass spectral analysis with resolution >10,000 full-width at half-maximum where resolution = m/d m, with m being mass and d m the full width of the peak at half its maximum height (FWHM).


Sponsored by • 151 homogenate


Suspension of tissue cellular fragments and constituents obtained after the tissue is homogenized, lysed, sonicated and/or digested.


S38


Bioanalysis (2016) 8(21) Suppl. 1


future science group


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