Terms & Definitions • 36 basal value


Measured value (e.g., for a biomarker) before the administration of a drug or other therapy.


• 37 baseline The chromatographic signal of a system in the absence of an analyte.


• 38 batch


A number of study samples of unknown concentration along with the appropriate standards and quality control samples (QCs) that are processed at one time. See also “analytical run”.


• 39 bias


The difference between an experimental value and a nominal value expressed as a percentage, sometimes used as a measure of accuracy or trueness. Bias (%) = [(Experimental value - Nominal Value)/Nominal Value] × 100%.


• 40 bioanalysis


The quantitative or qualitative measurement of endogenous or exogenous analytes in biological matrices, including tissue, blood, serum, urine or other body fluids.


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• 41 bioavailability The fraction of a drug dose that reaches the systemic circulation unchanged.


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