The Bioanalysis Glossary • 120 enzyme-linked immunosorbent assay (ELISA)


A form of immunoassay where the enzyme is linked to a protein that can bind to a captured analyte and through the subsequent addition of the enzyme’s substrate generate a molecule that is detected using UV, fluorescence or luminescence.


• 121 epimer


Stereoisomer with more than one chiral center that differs in the configuration at only one center.


• 122 epitope


The part of an antigen that is recognized by the immune system (i.e., antibodies, B or T cells).


• 123 error


The difference between an estimate of a quantity and its true value. This difference (positive or negative) may be expressed either in the units in which the quantity is measured or as a percentage of the true value.


• 124 esterase


A family of hydrolase enzymes that react with esters to form an acid and alcohol. Their activity commonly requires inhibition for robust quantitative analysis of analytes in biofluids.


• 125 European Medicines Agency (EMA)


Regulatory body responsible for the protection of public and animal health in the European Union through the scientific evaluation and supervision of medicines.


• 126 excretion


The final elimination of a compound and its metabolites from the body’s systemic circulation via the kidney into urine and via bile into feces.


S32 Bioanalysis (2016) 8(21) Suppl. 1 future science group


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