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HEALTHY LIVING Stay Sharp as You Age


Want to have an exceptional memory in your 80s? Genes and brain chemistry play a part, but so does lifestyle. ::


BY VERA TWEED W


e expect memory to fade as we get older, but SuperAgers — a term coined by


researchers — are defying the odds. They’re individuals who are


over 80 years old with exceptional memory, comparable to or better than people in their 50s and 60s. They’re often described as


being surprisingly “sharp as a tack” despite their advancing years, says Emily Rogalski, Ph.D., director of the international SuperAging Research Initiative and a professor of neurology at the University of Chicago. The initiative has tracked more


than 400 SuperAgers over the last two decades and plans to enroll a total of 500 participants across diff erent sites in North America. These SuperAgers are challenging common notions of what a very long life can look like. What sets SuperAgers apart?


Genes and brain chemistry play a part, but lifestyle does, too.


GENES, BRAIN STRUCTURE Brain scans and analyses of brain tissue have found some specifi c diff erences in genes and brain structure between SuperAgers and others in the same age group who are cognitively healthy but don’t have extraordinary memory. These include: Lower-risk genes: SuperAgers are


19% less likely to have the e4 variant of the APOE gene associated with the highest risk for Alzheimer’s disease, and 28% more likely to carry the e2 variant of the APOE gene associated with the lowest risk. Less brain shrinkage: With age,


86 NEWSMAX MAXLIFE | OCTOBER 2026


brain volume shrinks at the rate of about 2.24% per year in cognitively healthy people. In SuperAgers, it shrinks at less than half that rate, at 1.06% per year. Greater regeneration of brain


cells: SuperAgers produce at least twice as many new neurons in the hippocampus area of the brain as cognitively healthy people the same age. However, genes and brain


structure aren’t the only factors that determine the fate of our memory. “There are tremendous opportunities in exploring the things that we can change within our life,” Rogalski tells Newsmax, “rather than saying, ‘Ugh, I picked the wrong parents.’”


BEING SOCIAL SuperAgers avoid isolation and loneliness by being social, even if they outlive their peers by many years. “That’s a good adage for folks who want to think about what they can do today,” she says. The oldest SuperAger lived to 111.


But she continued to develop new social connections, not only with younger adults of advanced age but also with younger generations. “Another feature that we see in


our SuperAgers is this adaptability,” says Rogalski. “Some of those intergenerational connections, I think, are important.” Conversations with others of any


age are benefi cial because they are emotionally helpful and challenging as a mental exercise. “You talk about diff erent topics,” she says, “and you have to think in diff erent ways.”


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