The Peaceful Pill eHandbook The DDMAPh ‘5-drug’ Mix
A further improvement to the Lethal Drug Mixture was made in 2020 with the addition of a 5th drug, phenobarb. Phenobarb (Lu- minal) is a barbiturate that is still in wide use as an anticonvul- sant. Phenobarb had been a component of the original 3-drug mix where 20gm was used. In the newer 5-drug mix, a smaller 5gm dose was added to the D-DMA mix. This was found to further ‘pull in the outliers’ and shorten the average time to death. In the first US study of 52 cases the average ‘time to sleep’ (TTS) decreased slightly, but the ‘time to death’ (TTD) was reduced to 1.3 hours with DDMAPh, and with further slight reduction to 1.1 hours when the digoxin was given earlier, D-DMAPh.
The 5-drug mix of DDMAPh contains:
• 20mg of metoclopramide & 8mg of ondansetron • 100mg of digoxin • 15gm of morphine • 1gm of diazepam • 8gm of amitriptyline • 5gm of phenobarb
