Amitriptyline is one of the most sedating of the TCAs and par- ticularly useful as a lethal drug. The drug is marketed as Endep or Elavil tablets. The amount required is 8 - 10 gm.
Preparation of Amitriptyline
The drug is usually packaged as tablets in 10, 25, 50 or 100mg amounts (Fig 12.1) and is usually supplied in packets of 50 tablets. Two packets of 100mg tablets is (100 x 100mg) or 10gm of the drug.
For a peaceful death, open the blister packs and place 200 of the 50mg tablets in a glass. Add enough water to cover the drug and with gently agitation allow the drug to dissolve.
Amitriptyline with metocloptamide, oxazepam and Gin
NOTE: In the accompanying ‘Preparing Amitriptyline’ video the quantity of amitriptyline is given as 5gm. Current editions of the Handbook now have revised this to 8 - 10gm.
