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46 ANTI-AGEING


Face sculpting with rosewood biofunctional


Anne Clay Viardot, Christophe Capallere, Florian Labarrade, Yolene Ferreira, Isabelle Imbert - Ashland


Liftyl™ biofunctional is a premium rosewood extract to visibly lift and redefine facial contours, and an alternative to retinol with similar-proven efficacy and no irritation side effects. The extract is based on the latest genomic research in facial morphology and face sculpting. Facial morphology refers to a series of many different complex traits, each influenced by genetic and environmental factors. The shape of the face is genetically determined, and much research has been devoted to the study of facial morphology genes.1 Recent work, including genome-wide association studies involving thousands of participants, has identified many genetic loci influencing facial shape and contours.2,3


healthy tropical forest ecosystems and provide important resources for forest-dependent indigenous and local communities.


Upcycling wood chips from rosewood essential oil The rosewood extract is obtained from the species Aniba rosaeodora sustainably grown in plantations in Peru with full traceability and control over the entire supply chain from planting, growing, and harvesting the rosewood, to processing the essential oil by steam distillation without adding processing aids or any other chemical during the process. Wood chips depleted in oil are used for


Following


comprehensive ethno-genomic research in facial morphology, the extract has been evaluated on key influential markers modulating facial morphology and clinically tested on Caucasian and Asian skin.


The face sculpting movement This rosewood extract leverages the face sculpting consumer trend powered by influencers worldwide. According to TikTok, face sculpting is one of the hottest skincare trends. Lately, it is impossible to scroll through beauty-related videos on TikTok without seeing various ‘face lifting’ or ‘sculpting’ techniques. Face sculpting tools, such as Gua Sha, went viral on TikTok and are meant to mimic the effects of a lifting, firming, tightening facial, all in a matter of minutes and achieved in the comfort of one’s home. While Gua Sha has gained high popularity


among women today, the procedure has an ancient history in China. Gua Sha has been extensively leveraged by the ancient Chinese as a traditional practice used 700 years ago in the Ming Dynasty between 1368-1644. The Gua Sha practice is known for treating the body holistically: the Gua sha creates a friction and supports the notion that it boosts circulation, leading to a good health.


Rosewood: a noble wood prized for sculpture The rosewood is a tropical tree native to South America, India, Pakistan, and Madagascar. The wood from the rosewood tree is highly prized for its beauty, workability, and durability, which is ideal for making high-end musical instruments and furniture, such as classic


PERSONAL CARE July 2023


the extraction of rosewood by supercritical CO2 extraction using a bio-based cosolvent. Rosewood is part of a circular economy model, creating value out of a by-product, with a minimal use of natural resources and supporting the local and rural industry.


Key influential markers associated with face sculpting and skin ageing Ashland scientists used in silico


research to explore and map all markers (genes, proteins, RNAs) involved in face sculpting and


then to study the expression of some


style Hongmu in China. The growth in the global demand for over the past decade has brought many rosewood species to the brink of extinction. Another reason rosewood is desired is for the benefits of its essential oil that is extracted from the wood by steaming chips of rosewood. The fragrant oil is used in high end fragrances, aromatherapy, holistic treatments, and in cosmetics for its rejuvenating skin benefits. It is said to help with the healing of scars, acne, and stretch marks. The alluring fragrance of rosewood essential


oil made demand skyrocket, especially during the 18th century in the field of perfume- making. Rosewood is now protected by CITES (Convention on International Trade in Endangered Species of Wild Fauna and Flora) to preserve this rare and noble wood. A CITES- protected rosewood is a sustainable rosewood: CITES ensures the traceability from the tree plantation to the final manufactured product. The regulation of most internationally


traded species of rosewood can help maintain


markers in Asian and Caucasian skin, as well as their expression in aged skin. Firstly, data mining was used to identify key


influential markers related to face sculpting. Data mining is the process of using computers to explore and analyze, by automatic or semi- automatic means, large amounts of data in order to discover useful patterns, trends, or relationships.4 In silico research was used to explore


influential markers related to face sculpting in a large amount of data published in the scientific literature. Data mining revealed around 300 markers related to face sculpting and relationships between these markers (Figure 1). Data mining helped identify some genetic


determinants of the shape of facial contours from genome-wide association studies. Some components related to face sculpting were shown to be specific to certain ethnicities, and/ or specific to certain regions of the face, such as the cheeks or the lip corners. In vitro and ex vivo studies were carried out


to confirm that these markers were expressed in human skin, and that their expression was


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