The Bioanalysis Glossary • 368 ruggedness


The capability of a method to maintain adequate performance under irregular, extraneous influences on operational parameters.


• 369 r-squared


A term, often referred to as the correlation coefficient, used to assess the fitness of a linear relationship when performing regression.


• 370 salting out assisted liquid–liquid extraction (SALLE)


The extractive process by which a solution is supersaturated with salt to cause the formation of a biphasic system between a water sample and a water miscible sample. Analytes partition between the two phases, and typically the organic phase is taken for analysis.


• 371 sample


A generic term encompassing calibrators, controls, blanks, unknowns and processed samples.


• 372 sample diluent


Aqueous or organic fluids used to dilute the analyte prior to the analytical process (e.g., chromatographic separation, derivatization, binding to a receptor or antibody).


• 373 sample pretreatment


A process whereby fluid or tissue samples are homogenized, lysed, digested, sonicated, pulverized or extracted prior to analysis.


S92


Bioanalysis (2018) 10(21) Suppl. 1


future science group


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