Terms & Definitions
• 23 antigen A substance eliciting the formation of antibodies in a suitable host.
• 24 antisense oligonucleotide
A short nucleotide polymer that can bond to mRNA and block the process of gene expression.
Sponsored by • 25 aptamer
Nucleic acid molecule engineered to bind to various molecular targets. The mode of action of an aptamer is dependent upon its shape but not its sequence.
• 26 aqueous normal-phase liquid chromatography (ANP-LC)
A variant of normal-phase liquid chromatography (in which the stationary phase is more polar than the mobile phase) for which the mobile phase components and additives are water-miscible. Hydrophilic interaction liquid chromatography (HILIC) and chromatography on silica hydride-based phases are popular examples of ANP-LC.
• 27 archive
Collection and storage of records and specimens for a defined period of time. Typically as part of regulatory compliance and requiring security.
• 28 area under the curve (AUC)
The area under the plot of matrix (e.g., plasma) concentration of drug against time after drug administration, linked to bioavailability measurement.
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