Terms & Definitions • 323 precision


The proximity of agreement (i.e., degree of scatter) among a series of measurements obtained from the same homogenous sample under controlled assay conditions. Precision is defined as (standard deviation/ mean) and expressed in percentage. Three levels are are distinguished by the most important validation guidelines: „ Repeatability;


„ Intermediate precision; „ Reproducibility.


• 324 preclinical trial A study to test a drug, procedure, or medical treatment in animals.


• 325 precursor ion


In mass spectrometry, an electrically charged molecular moiety that may dissociate to form fragments, one or more of which may be electrically charged, and one or more neutral species. Also called “parent ion”.


• 326 predictive metabolomics


Prediction of the functional value of a treatment by means of multivariate analysis using metabolome data (metabolite signatures) as the explanatory variable.


• 327 predose sample


Biological sample, typically plasma, that is taken from the test subjects prior to receiving the study drug(s).


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