The Bioanalysis Glossary


Terms & Definitions • 132 enzyme-linked immunosorbent assay (ELISA)


A form of immunoassay where the enzyme is linked to a protein that can bind to a captured analyte and, through the subsequent addition of the enzyme’s substrate, generate a molecule that is detected using UV, fluorescence or luminescence.


Sponsored by • 133 epimer


Stereoisomer with more than one chiral center that differs in the configuration at only one center.


• 134 epitope


The part of an antigen that is recognized by the immune system (i.e., antibodies, B or T cells).


• 135 esterase


A family of hydrolaze enzymes that react with esters to form an acid and alcohol. Their activity commonly requires inhibition for robust quantitative analysis of ester analytes in biofluids.


• 136 European Medicines Agency (EMA)


Regulatory body responsible for the protection of public and animal health in the European Union through the scientific evaluation and supervision of use of medicines.


• 137 excretion


The final elimination of a compound and its metabolites from the body’s systemic circulation via the kidneys into urine, and via bile into feces.


S38


Bioanalysis (2018) 10(21) Suppl. 1


future science group


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