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New molecule


Mibelle Biochemistry will launch CM-Naringenin-Chalcone (TCM-NC), a semisynthetic active derived from the polyphenol naringenin-chalcone, which naturally occurs in the peel of citrus fruits and tomato skin. Naringenin-chalcone is reported to have potent anti-inflammatory properties. Based on this information, CM-Naringenin-Chalcone, a new compound of improved stability and water solubility has been developed. The new molecule was studied for its beneficial effects on rosacea skin. Recent research reveals that an overproduction of cathelicidin LL37 in keratinocytes plays a major role in the development of this inflammatory skin disorder. In an in-vitro study TCM-NC was shown to reduce the LL37-induced release of inflammatory cytokines in human keratinocytes. A placebo controlled clinical study performed on female Caucasian volunteers with mild rosacea skin confirmed a visible reduction in blood flow and rosacea redness after 56 days of treatment. TCM-NC is a promising new cosmetic active ingredient suitable for the treatment of sensitive skin, such as rosacea.


Mibelle Biochemistry, Stand 1G50 Sytheon promote skin protection


HSS for the stabilisation of photosensitive compounds and compositions. This new patent targets the stabilisation of photochemically unstable compounds such as; Avobenzone, Retinol, Vanillin and water soluble dyes. It broadens the scope of an earlier US patent issued to Sytheon on this technology and this new ingredient will be presented at in-cosmetics 2014.


Sytheon will also showcase Synastol™ TC. Synastol™


TC is a defined edible fruit extract from Terminalia chebula and is an excellent all round antioxidant, anti- inflammatory and anti-glycation agent. A recent clinical


trial performed using 1% Synastol™ volunteers aged between 41 and 65 applied a cream containing 1% Synastol™


resulted in excellent broad spectrum anti-ageing results. 17 female TC twice a day. After 12


weeks, qualitative values showed a statistically significant improvement in fine lines & wrinkles, skin tone and dark circles. Results were further quantified by silicone replica analysis and resulted in more than 20% reduction in wrinkle depth and over 25% improvement in skin roughness.


Sytheon, Stand 1J40 NH Butters


Brasca will showcase NH Butters at in-cosmetics 2014. NH Butters are a selected range of non- hydrogenated vegetal butters. The 100% mechanical soft manufacturing method allows the preservation of the integral properties of the natural lipidic plant components, avoiding any destructive process.


The unique plant lipids, technologically enhanced by Olifeel®


Pearls patented triglycerides,


boast high performance skin feel properties while unveiling surprising new benefits. Among these are high resistance to oxidation, high drop point value (around 50˚C), good organoleptic properties (low odour, low colour) and trustable batch consistency. Compatible with all cosmetic ingredients, NH Butters add exclusive features in terms of texture and structure to the finished product, and help stabilise the formula due to the presence of natural triglycerides. Choose your easy-to-use butter from Maracujia, Baobab, Argan, Avocado, Apricot and many more.


Brasca, Stand 4F72 Specifeel® NH Butter Argan


Sytheon Ltd has been granted a new US patent utilising Synoxyl®


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