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On-line TOC Analyser Designed for Pure Water Applications
Shimadzu has released the TOC-1000e, the first analyser in the eTOC series of on-line TOC analysers designed for pure water applications. The eTOC series’ main focus is on miniaturisation, high sensitivity and a mercury-free oxidation technique. The pioneering TOC-1000e system has the world’s smallest and lightest cabinet and provides high-sensitivity detection, making it ideal for fields requiring high-purity water applications. This covers manufacturing, including pharmaceuticals, semiconductors, food & beverages, chemistry and precision equipment.
Shimadzu’s world-leading TOC analysers are well-suited to laboratory and on-line analysis of environmental and wastewater. The eTOC series will be Shimadzu’s first on-line TOC analyser designed especially for pure water measurements.
The TOC-1000e provides enhanced robustness in the ultra-low measurement range. With its small footprint of less than A4 size, it can be installed flexibly - either as table-top, wall-mounted or pole-mounted.
Conventional TOC analysers for pure water utilise mercury UV lamps as the light source within the instrument. To provide a more environmental-friendly alternative, the eTOC series is the first analyser in the world to use an excimer (short for ‘excited dimer’) lamp rather than a mercury lamp.
The ‘Active-Path’ flow line design maximises lamp power by integrating the sample flow channel and the light source. This minimises sample residue in the flow channel and eliminates interfering air layers, so high sensitivity is maintained over long-term use. This new design also contributes to making the eTOC series instruments small and light.
eTOC’s highly sensitive UV oxidation-conductivity method for ultra-pure water monitoring is compliant with regulatory requirements such as the United States (USP) and the European Pharmacopeia (EP). Inbuilt security functions including user authentication and audit trail, support compliance with regulations such as FDA 21 CFR Part 11. The LabSolutions software platform provides integrated management of the measurement data together with data and electronic signature functions (ER/ES) from laboratory TOC analysers and other analytical instruments.
More information online:
ilmt.co/PL/e92P 55152pr@reply-direct.com
Complete Pumping Solutions for Biotech and Pharma Industries
Unibloc’s patented LABTOP pumping solution addresses the challenges faced by the biotechnology and pharmaceutical industries relating to cleanability, shear sensitive transfers scalability and pilot applications that other types of manufacturing don’t require. LABTOP features a compact and highly-mobile design that makes your pumping activities simple and efficient. It is also self- sustainable, so there’s no need for other pieces of equipment to complete a processing task.
Unibloc’s bubble traps are also widely used throughout the chromatography, pharmaceutical and biotech industries. The traps are used as air separators to remove pockets of air, so they don’t hinder critical processes. The simple and ultra-clean design allows for easy installation and maintenance. Unibloc bubble traps feature electropolished surfaces, USP Class VI elastomers and comprehensive documentation packages, and are made to accommodate specific application requirements with custom port sizes and configurations including new septic connections with 8” drain angle, guaranteeing full and secure cleanability.
More information online:
ilmt.co/PL/1dZO and
ilmt.co/PL/zJVy 55125pr@reply-direct.com
How Important are AAV Reference Materials in Gene Therapy?
Amsbio has announced a new range of AAV reference materials of full capsids and empty capsids of 6 different serotypes. Critical to enable meaningful comparisons between research studies and clinical trials, these well-characterised reference standards are extensively quality analysed with molecular based assays and transmission electron microscope.
Gene therapy researchers have long expressed the importance of well characterised AAV reference materials. Recombinant adeno-associated virus (rAAV) is a widely used gene delivery tool for research and clinical applications. Following the US Federal Drug Administration gene therapy CMC guidance published in January 2020, commercially sourced, well-characterised AAV reference materials are one of the cited reference materials for gene therapy.
Amsbio’s AAV reference materials (full capsids) with accurate vector genome concentration can be used in qPCR-based vector genome quantification. Additionally, these AAV reference materials are well characterised for full-to-empty capsid ratio. AAV reference materials are available from Amsbio in AAV1, AAV2, AAV5, AAV6, AAV8 and AAV9 serotypes.
Adeno-Associated Virus are also known to produce empty particles without payloads. These high purity, quality certified AAV empty capsids reference materials can be used as controls and standards in assays, including HPLC and ELISA, Amsbio offer these AAV empty capsid reference materials in AAV1, AAV2, AAV5, AAV6, AAV8 and AAV9 serotypes.
More information online:
ilmt.co/PL/QaRX 55316pr@reply-direct.com
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