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New Fluorescence Cell Counter Redefi nes Automated Cell Counting
CytoSMART Technologies has announced the release of its fi rst fl uorescence cell counter. The CytoSMART Exact FL is an automated, dual fl uorescence cell counter with an expanded fi eld of view and unmatched performance.
Although the system’s footprint is very small, its specifi cations rival most, if not all alternative automated cell counters. The CytoSMART Exact FL sets new standards in terms of accuracy, speed, and performance thanks to a wide range of technological advancements. The improved specifi cations include not only an advanced 6.4-megapixel CMOS camera, but also ultrafast autofocus, high magnifi cation and high contrast lenses, increased measuring volume, and super robust image recognition by Artifi cial Intelligence (AI) algorithms.
The CytoSMART Exact FL calculates the exact number of cells in a sample and provides a reliable assessment of key cellular parameters, including cell viability and transfection effi ciency. The increased magnifi cation and high resolution offer an unprecedented level of detail, distinguishing between whole cells and cell debris and counting even the smallest of mammalian cells (CAR-T cells, stem cells, PBMCs).
“We are truly excited to launch this dual fl uorescence cell counter with an optical system of unmatched power. This innovative device can be used for a number of standard laboratory applications. The CytoSMART Exact FL can count cells using a bright-fi eld channel, while simultaneously assessing viability and transfection effi ciency with two fl uorescent channels. It can also ease the counting of hard-to-detect primary cells or quantify multiple cell types in one sample. Another fascinating feature of our devices is the introduction of add-on modules, which enable customers to expand the application range of their device allowing them to also count organoids,” said Joffry Maltha, CEO at CytoSMART Technologies.
The main features and advantages of the CytoSMART Exact FL are: 6.4 Megapixel camera; hHigh contrast and high magnifi cation optics; ultrafast autofocus; dual fl uorescence cell counting; AI-powered image analysis software; lower coeffi cient of variation with increased counting volume option and a multi-count feature; ability to add Organoid counting module; very cost-effi cient thanks to its compatibility with reusable or disposable counting slides; secure cloud data storage.
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Powerful Cameras for Life Science Imaging Applications
Two new DP series cameras from Olympus share advanced, time-saving features while enabling users to choose the most suitable model based on the level of resolution required. With 4K ultra-high-defi nition image quality, the DP28 camera enables users to share and review sample images in fi ne detail while the DP23 camera’s 6.4-megapixel resolution and 45 frames per second (fps) frame rate make it easy to quickly capture images with the detail needed for most life science imaging applications.
The DP28 camera’s 8.9-megapixel CMOS image sensor, global shutter and 4K resolution at 32 frames per second (fps) provide the outstanding image quality required. For smooth images of fast-moving samples, the camera can capture full HD live images at 64 fps, matching the maximum frame rate of a standard monitor. If 4K resolution is not required, the DP23 camera balances speed and HD resolution for fast, effi cient imaging and analysis.
The DP28 and DP23 cameras can capture images with a fi eld of view up to FN25, so users can see more of their sample at once with in-focus images from the centre to the periphery for effi cient imaging. And like all cameras in the DP series, both reproduce colours accurately, so stained specimens look the way they are expected to.
Key features include Olympus smart image averaging, which suppresses noise while maintaining a high frame rate and eliminating artifacts to produce clear images, high contrast mode to capture clear images of dim samples and focus peaking to quickly identify which areas of the sample are in focus.
All critical data, including images, annotations and live measurements, can be displayed and shared locally or remotely. Network image sharing enables users to review samples with offsite colleagues, saving time. The camera’s control module supports NIST, GDPR and optional antivirus software for safer data sharing.
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