Microscopy & Microtechniques 91 Digital Microscope Simplifi es Cell Culture Checks
Mateo TL, a new digital transmitted light inverted microscope for routine cell culture, has been launched by Leica Microsystems. With Mateo TL, lab members can easily and comfortably check and document cell growth. By consistently measuring confl uency, they can be confi dent in the readiness of their samples for downstream experiments.
“Good cell culture sample preparation is an important starting point for every successful experiment, and now it has become even easier and more reliable with Mateo TL,” said James O’Brien, Vice President of Life Sciences and Applied Microscopy at Leica Microsystems.
“During the sample preparation process, subjective judgements are often used for sample readiness assessments, which can compromise the quality and the outcome of experiments, said Jennifer Kulhei, Product Manager, Life Science and Research Microscopy at Leica Microsystems.
With Mateo TL, labs can establish a reliable criterion for evaluating confl uency, improving experiment reproducibility. The confl uency algorithm measures the percentage of cell coverage in the image, enabling consistent measurements across multiple users. Additionally, users can work in a sterile environment to minimise contamination risk by placing Mateo TL directly under the fl ow hood, ensuring the integrity of their experimental outcomes.
Mateo TL is a user-friendly microscope that is easy to set up and use, even for non-experts. It is designed to support cell culture checks for a range of users, from principal investigators and postdoctoral researchers to PhD and master’s students, as well as lab technicians, all of whom may have varying levels of microscopy expertise. The microscope can be set up in less than a minute, providing a ready-to- use system that team members can start working on immediately. Once set up, cell culture checks are made easy for the whole team with Mateo TL’s user-friendly software interface, enabling simple live viewing and image acquisition.
In addition to its user-friendly design, Mateo TL streamlines cell culture checks by improving effi ciency and convenience. With its convenient fi le sharing capabilities, smart light and camera settings, and enhanced ergonomics, Mateo TL empowers teams to spend less time on routine cell culture checks and more time on their experiments.
More information online:
ilmt.co/PL/v1B 59953pr@reply-direct.com CE-IVD Certifi ed Digital Live Microscope for Clinical Use
German digital microscopy company PreciPoint has announced the launch of its iO:M8 Digital Live Microscope, which recently received CE-IVD certifi cation under the new IVDR regulation. The microscope is designed to digitise intra-operative examinations during cancer surgery and provides high-resolution, real-time images of samples. The iO:M8 can accommodate up to four slides simultaneously, making it easy to use and providing pathologists with more information about the tissue removed during surgery. PreciPoint has received numerous awards and recognition, including Top Employer 2023 and Top100 Innovator 2022, for its bespoke solutions to bridge the gap between digital workfl ows and pathologists.
More information online:
ilmt.co/PL/WM7n 60111pr@reply-direct.com
Optical Sectioning Device for High-Contrast and Blur-Free Imaging
Olympus announces the latest addition to its product lineup - the SILA Optical Sectioning Device. Designed to empower researchers and professionals in obtaining high-contrast images from deep within their samples, this cutting-edge device revolutionises optical sectioning capabilities.
The SILA optical sectioning device combines speckle illumination and HiLo microscopy techniques to deliver exceptional imaging results. By capturing two illuminated images and employing advanced mathematical processing algorithms, out-of-focus light is effectively removed, resulting in high-contrast images. What sets this technology apart is its user-friendly nature, requiring no specialised calibration and making it accessible to users at all skill levels.
SLIDEVIEW™ VS200 v. 4.1 software seamlessly integrates with the SILA optical sectioning device, enabling users to effortlessly acquire optical sectioning images. Regardless of imaging depth, the software ensures consistent optical sectioning capabilities, allowing users to capture stunning images even from deep within their samples.
One of the key advantages of the SILA optical sectioning device is its versatility and compatibility with existing VS200 systems, including those equipped with a slide loader. Its compact design allows for easy installation onto the scanner’s fl uorescence illuminator. Moreover, the device is compatible with a wide range of sample types, including cleared and fi xed cells and tissues thicker than 100 microns, accommodating various magnifi cation requirements.
Conventional detection methods often fall short in identifying transparent and morphologic features on samples, potentially missing critical targets. However, SLIDEVIEW v. 4.1 software now incorporates TruAI™ technology, which excels at accurately segmenting these features and distinguishing them from visually similar structures.
To streamline data management and reduce the data burden, TruAI leverages its selective scanning mode, intelligently identifying the sample area and skipping irrelevant sections. This optimisation of data handling encompasses storage, image uploading, and sharing, enhancing effi ciency throughout the workfl ow.
Users can seamlessly upload their images to the database, effortlessly differentiate between users, and leverage offl ine visualisation and annotation tools for enhanced analysis and collaboration.
More information online:
ilmt.co/PL/mVRB 60471pr@reply-direct.com
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