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Low-Flow HPLC Columns for Proteomics
With its distinct micro-pillar separation design, the Thermo Scientific µPAC Neo HPLC Columns offer researchers the ability to delve deeper into proteomics samples. These columns allow for precise identification of peptides, determination of protein quantities, and discovery of disease biomarkers and post-translational modifications.
The latest inclusion in the product line is the low-load trapping column of µPAC Neo, designed to cater to the tiniest sample sizes in single-cell proteomics separations. This column comes equipped with built-in nanoViper connections to the Vanquish Neo UHPLC systems, which offers seamless usability and mitigates the risk of errors. All users of µPAC Neo columns can experience the advantages of consistent column reproducibility, leading to more dependable data analysis and result reliability.
The complete range of µPAC Neo columns presents a variety of options to cater to different proteomics research requirements. These include a 50 cm µPAC Neo column that is well-suited for routine proteomics, a 110 cm µPAC Neo column designed for comprehensive proteomics investigations, and a 50 cm µPAC Neo low-load column that is specifically tailored for single-cell proteomics. In addition, the µPAC Neo low-load trapping column provides support for single-cell proteomics separations, complete with built-in nanoViper connections to Vanquish Neo UHPLC systems for greater ease of use and reduced risk of errors. With this diverse range of options, researchers can choose the most appropriate column for their specific proteomics analysis needs.
The manufacturing process of µPAC Neo columns involves micromachined etching of silicon wafers, leading to the creation of precise and uniform separation paths. This results in an exceptional level of consistency between columns and prolonged column lifetimes, which is particularly beneficial for proteomics research. These columns offer greater column-to-column reproducibility compared to packed-bed columns, making it easier for researchers to develop and validate methods and analyse larger sample batches with more confidence.
More information online:
ilmt.co/PL/WMxd New GPC/SEC Combination Detector
Testa Analytical Introduces an advanced detector package combining Multiple Angle Light Scattering and Differential Refractive Index (MALS/DRI) for more demanding Gel Permeation Chromatography (GPC/SEC) Applications.
MALS is a reliable detection technique for GPC/SEC that delivers precise molecular weight data for a range of molecules, from small to large. It has proven to be effective in polymer, protein, and polysaccharide applications, earning a reputation as a trusted method.
To achieve the highest level of accuracy and sensitivity, it is necessary to combine MALS with a DRI detector. The DRI detector is specifically designed to provide concentration information that is detected at the same wavelength as MALS, resulting in more precise and sensitive results.
Testa Analytical has introduced the new COMBO-TWO MALS/DRI detector package, which combines a high-performance 7-angle MALS and an ultra- stable DRI detector that operate optimally with an integral 640nm light source. This perfectly matched combination offers exceptional results with the lowest possible delay volume between the MALS and DRI detectors. The unique COMBO-TWO is fully compatible with all commercial GPC/SEC systems and has high thermal stability, operating from room temperature up to 80°C. Obtaining highly accurate and reliable MALS and DRI data is easy - simply inject your sample into the low-volume flow cell.
More information online:
ilmt.co/PL/9RGD Real-Time Cloud-Native Lab Management System Monitoring
The waters_connect™ System Monitoring, a Software-as-a-Service (SaaS) application from Waters Corporation is designed to help laboratory managers and analysts monitor the real-time status of any chromatography instruments running on Waters™ Empower™ Software.
This cloud-native application is especially beneficial for high-volume quality assurance/quality control (QA/QC) laboratories, as it can reduce the turnaround time of product release samples and provide an understanding of instrument history and usage levels.
“The pharmaceutical industry relies heavily on Empower Software to ensure that an uninterrupted supply of medicines reaches pharmacy shelves and the patients who need them,” said Dave Leitham, Vice President, Connected Science, Waters Corporation. “The ‘always-on’ waters_connect System Monitoring dashboard allows lab managers and analysts to check in on their instrument fleet from anywhere, anytime and helps them improve product release timelines and delivery schedules.”
The waters_connect System Monitoring application is now available in Europe and North America. More information online:
ilmt.co/PL/Z4JB
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