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Entry-Level Microplate Heat Sealer for Efficient Sealing
The Ultraseal™ Lite from Porvair Sciences is a semi-automatic microplate sealer that is designed to meet the needs of labs with low to medium throughput processing requirements of up to 6 plates per minute. The device is user-friendly, making it easy to operate, and offers a cost-effective solution for efficient microplate sealing.
An ideal solution for labs with limited space, the Ultraseal™ Lite has a compact design that allows it to fit into tight spaces such as lab benches or inside fume hoods. Despite its small size, it is a powerful and reliable device that provides efficient microplate sealing.
With its powerful 450W heater and strong sealing action, the Ultraseal™ Lite can achieve high integrity sealing of various types of microplates, including deep well, shallow well, low profile deep well, filter, and assay plates that conform to the ANSI/SLAS standard format. The device’s advanced features ensure a strong and reliable seal, providing an efficient and effective solution for labs requiring high-quality sealing.
By using heat seal films and foils, the device can provide either permanent or peelable seals for commonly used microplate types, such as polypropylene, polystyrene, and polyethylene. This feature ensures that labs can effectively seal microplates with different materials, providing convenience and versatility for a range of laboratory applications.
Using Porvair seals, the Ultraseal™ Lite can seal most polypropylene plates in less than 3 seconds each. Seal times and temperatures are fully adjustable through the control touch screen, allowing for flexibility in sealing parameters. After sealing, the plates are automatically ejected from the device, making the process fast and efficient.
The Ultraseal™ Lite can operate on 120 and 240 volt alternating current, 50/60 Hz mains supplies, without requiring a power transformer, due to its dual voltage capability.
More information online:
ilmt.co/PL/06zA 59933pr@reply-direct.com
Advanced Technology for Creating Vascularised Kidney Organoids
AMSBIO recently conducted an interview with Professor Ryuji Morizane, a distinguished expert in renal research at Harvard Medical School. Professor Morizane’s groundbreaking research, which combines organoid and bioengineering technology, has led to the development of kidney organoids that incorporate a vascular system.
To support this innovative work, Professor Morizane’s research team employs StemFit® , a chemically-
defined culture medium without human or animal-derived components, for the embryonic (ES) and induced pluripotent stem cells (iPSC) used in the research. Moreover, StemFit®
is a feeder-free medium.
In discussion about his research - Professor Morizane commented: “There were many challenges we had to overcome to reliably produce vascularised renal organoids. In the past, we used to culture hPSCs with feeder cells, however frequent passaging and the removal process of feeder cells often lead to variations in cell quality. Using StemFit®
culture medium, has allowed us to eliminate the use of
feeder-culture, meaning we can produce a larger stock of iPSCs. This, combined with frequent checking of progenitor cell differentiation efficacy, has helped our researchers reduce batch-to-batch variation. Switching to StemFit®
has also improved cell viability and growth, enabling us to improve gene-editing efficacy, and the production of more cells for experimentation.”
He added: ”Our renal organoid technology shows great promise for use in disease modelling and toxicity testing. In the future, I would like to focus on translational research such as drug screening using kidney organoids – and also consider clinical applications. Here the challenge is to produce high-quality cells used for transplantation. For these new applications it is necessary that we develop cost-efficient culture methods to produce iPSCs and the differentiation protocols of organoids.”
AMSBIO’s StemFit®
series of chemically-defined media, which are free of animal-derived components, have been demonstrated to effectively maintain induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) in feeder-free conditions throughout the stem cell culture reprogramming, expansion, and differentiation phases. StemFit®
efficiency, from basic research to clinical applications. To read the interview in full please visit
ilmt.co/PL/GbQV More information online:
ilmt.co/PL/D3bV
is available in both research and GMP grade formulations, and is the market
leader in colony-forming efficiency, with lower media volume consumption compared to leading competitors, resulting in the most cost-effective colony expansion. StemFit®
is a component of AMSBIO’s Stem Cell Synergy Solution product line for streamlining and improving ES/iPS Cell Culture
59900pr@reply-direct.com
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