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Magnetic Resonance MQC Benchtop NMR System for Quality Control of their PVC-Based Products
Oxford Instruments is pleased to report that Vinyl Compounds have purchased a new MQC Benchtop NMR system. This underscores their commitment to the best quality products through investment in the latest QC instrumentation. With 35 years in the PVC compound industry, Vinyl Compounds produce an extensive range of rigid, flexible and specialty grades of PVC. These products range from standard industry formulations to highly technical and customer bespoke formulations. Materials will be formulated to meet the chemical, mechanical and physical properties required of the final product. Through the company's continual investment programme, they have established a modern manufacturing facility capable of producing in excess of 60,000 tonnes of PVC compound and dry blend per annum.
The standard industry test to measure softness requires a 24-hour conditioning period. While this is still performed, Vinyl Compounds have developed their own in- house procedure whereby they can predict the softness level of the product in a matter of minutes using their MQC benchtop NMR system. Having built up a library of data, they have shown a linear correlation between plasticiser content as measured by NMR with the 24-hour test. This means they can rapidly test materials for the customers to ensure a rapid turnaround, a responsiveness that keeps them in the forefront of PVC suppliers.
Vinyl Compounds' Commercial Director, Richard Loynes, commented on the company's latest investment: "Having been users of Oxford instruments' robust and reliable NMR technology for over thirty years, it was natural for us to purchase a new MQC system. It reflects the company commitment to our customers where we aim to continually provide improved support through investment in the latest technology available to us." Oxford Instruments' latest benchtop NMR analyser offers fast, reliable Quality Control measurements in a compact, up-to-the-minute package, ideally suited to the needs of Vinyl Compounds. The MQC features a compact magnet for minimum benchtop footprint; modular design for easy serviceability; upgradeable firmware, and software self-diagnostics to aid servicing. The MQC uses Oxford Instruments' acclaimed MultiQuant and EasyCal software packages, allowing simple calibration and measurement of up to four constituents in samples. Every MQC system is supplied complete with application specific software and hardware.
Circle no. 133
Analytical Balances Provide Precision and Value
Adam Equipment offers PW analytical balances as a quick and easy way to measure to 0.1mg. The PW analytical balance features durable, solid metal construction, standard internal motorised calibration, and a large, easy-to-read backlit display with on-screen text prompts to help the user set up the balance quickly. The simple, intuitive user interface is ergonomically designed with all main functions accessible with a touch of the button. Highlighted tare keys stand out for easy access and recognition, while other buttons access set-up functions, turn the balance on or off, send data to a printer, calibrate and change modes and weighing units.
The bi-directional RS-232 interface enables data transfer from the balance to printers or computers. This allows foolproof data recording and traceability, letting the operator focus on analysis rather than recording data. Other convenient features include built-in applications for density, percentage and check weighing, plus counting and dynamic or animal weighing. The PW offers 16 weighing units, including a custom unit. With models from 120g to 250g and readabilities at 0.1mg, there is a PW analytical balance available for most applications.
Circle no. 134
Innovative Glass Fibre
Porex Corporation has launched an innovative line of glass fibre designed to deliver precision, accuracy and reliability when used in the most challenging filtration, separation, extraction and purification procedures. Manufactured in various particle retention sizes and thicknesses, Porex BioDesign Glass Fibre helps prevent premature clogging and compromising flow rates when processing large volumes and challenging solutions. It can be used in a wide array of life science and diagnostic applications including spin columns, assay plates, purification kits and IVD sample wicks, absorbent pads and conjugate release.
“Porex is committed to developing innovative solutions that meet the needs of our healthcare and life science customers,” said William Midgette, President and CEO of Porex. “Our BioDesign Glass Fibre is just one of the many products that demonstrate our commitment to delivering high quality products that provide our customers with the peace of mind they deserve.”
Circle no. 135
High Performance Particle Sizing Enables Confident Decision Making from Drug Development to Manufacturing
Specified to meet the stringent requirements of today’s pharmaceutical industry for secure, reliable particle size analysis, the new Mastersizer 3000 laser diffraction system from Malvern Instruments provides a single platform that can be used throughout the drug development cycle, with easy transfer of methods from R&D right through to QC.
The Mastersizer 3000 delivers high performance across a very wide particle size range from 10 nm to 3500 microns, with faster-than-ever measurement times and robust, dependable results. Having the best quality data throughout the drug development cycle means critical decisions can be made quickly and with confidence.
The Mastersizer 3000’s Aero S accessory brings the advantages of dry powder dispersion to even the most fragile of pharmaceutical materials, including crystalline active ingredients. The challenge here is to apply enough energy to disperse the sample and loose agglomerates but not so much that breakage of primary particles starts to occur. The Aero S incorporates the very latest in dispersion research, enabling the Mastersizer 3000 to meet this need by applying gentle but highly effective dispersion, with no impaction surfaces. This results in efficient dispersion of even cohesive or delicate particles, without primary particle damage, and means quick and easy access to the particle size information of interest for an extended range of materials.
Whether measuring dry or wet, the Mastersizer 3000 provides embedded expert guidance and assurance, from method development through to routine measurement. During method development, real-time feedback from the Mastersizer 3000 simplifies the identification of a procedure that meets USP <429> and/or ISO13320 standards for repeatability and reproducibility. Such methods are then locked down for transfer or daily use assuring application of a consistent method, but beyond this Mastersizer 3000 provides continuous critical assessment of the measurement data. By alerting the user to any problem with the measurement it reduces the chance of poor quality data going undetected into the information chain.
Since Malvern takes the strict validation requirements of its customers very seriously, full IQ/OQ and PQ validation and documentation is automatically available. The Mastersizer 3000 software also takes full advantage of the security features in the latest windows operating systems to allow full compliance with CFR21 part 11.
Circle no. 136
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