table 2. Mycobactericidal Effects of Aldehyde-Based and Oxidizing High-Level Disinfectants Against GTA-Susceptible and GTA-Resistant Mycobacterium Isolates in Carrier-Disk Testsa
Product Tested
45 min 20 min
Mmas CIP 108297 (GTAS)
Cidex (1.5% GTA), 25°C 0 min
7.55±0.03 0
Aldahol (1.8% GTA) 20°C 0 min
15% Isopropanol, 25°C 0 min
7.55±0.03 0
7.55±0.03
Cidex OPA (0.3% OPA), 25°C 0 min 5 min
20 min 7.67±0.34 7.55±0.03
0
Reliance DG, 50°C 0 min 6 min
S40, 50°C 0 min 6 min
Resert XL, 25°C 0 min 8 min
7.45±0.01 0
7.45±0.01 0
7.55±0.03 0
Mmas CRM-0270 (GTAS)
7.30±0.06 0
7.30±0.06 0
7.30±0.06 7.77±0.00
7.30±.06 0
7.59±0.06 0
7.59±0.06 0
7.30±0.06 0
Mmas CRM-0019 (GTAR)
7.52±0.00 6.14±0.06
7.52±0.00 0
nd nd
7.52±0.00 0
8.31±0.00 0
8.31±0.00 0
nd nd
Mch ATCC 35752 (GTAS)
7.59±0.05 0
7.59±0.05 0
7.59±0.05 7.91±0.05
7.59±0.05 0
7.63±0.03 0
7.63±0.03 0
7.59±0.05 0
Mch 9917 (GTAR)
Mch Harefield (GTAR)
Mch Epping (GTAR)
6.91±0.11 7.34±0.01 7.44±0.11 4.59±0.28 3.74±0.00 5.77±1.3
6.91±0.11 7.38±0.12 7.44±0.11 4.57±0.17 2.96±0.09 5.94±0.35
6.91±0.11 7.38±0.12 7.44±0.11 6.89±0.02 7.45±0.14 7.52±0.17
6.91±0.11 7.38±0.12 7.44±0.11 0
0 0 0
6.49±0.00 7.63±0.06 7.46±0.00 0
0
6.49±0.00 7.63±0.06 7.46±0.00 0
0 0 0
6.91±0.11 7.38±0.12 7.44±0.11 0
0
M. bovis BCG (Pasteur) (GTAS)
nd nd
nd nd
nd nd
nd nd
nd nd
nd nd
nd nd
NOTE. GTA, glutaraldehyde; OPA, ortho-phthalaldehyde; CFU, colony-forming units; GTAR, GTA-resistant; GTAS, GTA-susceptible. nd,
not determined. aControl carrier tests using the GTA-susceptible isolate, M. massiliense CIP 108297, confirmed the neutralizing efficacy of the neutralizing broth with each disinfectant product. The detection limit of the carrier-disk tests is 1 CFU.
M. avium 104 (GTAS)
nd nd
nd nd
8.43 6.33±0.00
nd nd
8.43±0.03 0
8.43±0.03 0
nd nd
M. terrae ATCC 15755 (GTAS)
nd nd
nd nd
nd nd
nd nd
7.00±0.08 0
7.00±0.08 0
nd nd
788 infection control & hospital epidemiology july 2017, vol. 38, no. 7
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