from vap to vae 869
prior reports that the new VAE definition identifies only select cases of VAP and misses manyVAP cases thatwould have been captured with the pre-2013 definition. These findings suggest that this new surveillance definition may miss potentially clinically meaningful events that are important for driving infection prevention efforts.
acknowledgments
The authors wish to thank Ms Rebecca Brooks and Ms Lisa Teal for their assistance with data collection and Ms Grace Fulton for her administrative assistance. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Financial support: A.M.L. is supported by the National Center for Advancing Translational Sciences, National Institutes of Health (grant no. KL2TR001109). S.W.J. is supported by the National Institute of General Medical Sciences (grant no. K08GM109106-03). This work was supported by the Doris Duke Charitable Foundation (grant no. 2015213). Potential conflicts of interest: A.M.L. has received honoria from Destum
Partners and KPB Biosciences and research funding from GlaxoSmithKline. D.v.D. has served on the advisory boards of Actavis, Allergan, Achaogen, Shionogi, Tetraphase, Sanofi-Pasteur, Astellas, and Medimmune and has received research funding from Steris and Scynexis. D.J.W. is on the advisory boards of Pfizer and Merck. All other authors have reported no conflicts of interest relevant to this article.
Affiliations: 1. Division of Infectious Diseases, University of North Carolina
at Chapel Hill, Chapel Hill, North Carolina; 2. Department of Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, North Carolina; 3. Division of Pulmonary Diseases and Critical Care Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 4. Department of Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 5. North Carolina Jaycee Burn Center, Chapel Hill, North Carolina. Address correspondence to Anne M. Lachiewicz, MD, MPH, Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, 130 Mason Farm Road, Mail code CB# 7030, Chapel Hill, NC 27599-7030 (
anne_lachiewicz@med.unc.edu).
Received November 18, 2016; accepted March 13, 2017; electronically published April 17, 2017
Finally, during the final 18-month period, we used both defini- tions simultaneously so that the rates could be directly compared. In summary, our findings in a busy academic BICU confirm
© 2017 by The Society for Healthcare Epidemiology of America. All rights reserved. 0899-823X/2017/3807-0016. DOI: 10.1017/ice.2017.63
references
1. National Healthcare Safety Network. Device-associated module ventilator-associated event (VAE). Centers for Disease Control and Prevention website.
http://www.cdc.gov/nhsn/PDFs/pscManual/ 10-VAE_FINAL.pdf. January 2017. Accessed February 2, 2017.
2. Magill SS, Klompas M, Balk R, et al. Developing a new, national approach to surveillance for ventilator-associated events: execu- tive summary. Chest 2013;144:1448–1452.
3. National Healthcare Safety Network. Device-associated module PNEU: pneumonia (ventilator-associated [VAP] and non-ventilator- associated pneumonia [PNEU]) event. Centers for Disease Control and Prevention website.
https://www.cdc.gov/nhsn/pdfs/pscmanual/ 6pscvapcurrent.pdf. January 2017. Accessed February 2, 2017.
4. National Healthcare Safety Network. Key terms. Centers for Disease Control and Prevention website.
https://www.cdc.gov/ nhsn/PDFs/pscManual/16pscKeyTerms_current.pdf. January 2017. Accessed February 2, 2017.
5. Dudeck MA, Weiner LM, Allen-Bridson K, et al. National Healthcare Safety Network (NHSN) report, data summary for 2012, device-associated module. Am J Infect Control 2013;41: 1148–1166.
6. Magill SS, Li Q, Gross C, Dudeck M, Allen-Bridson K, Edwards JR. Incidence and characteristics of ventilator-associated events reported to the National Healthcare Safety Network in 2014. Crit Care Med 2016;4:2154–2162.
7. Lilly CM, Landry KE, Sood RN, et al. Prevalence and test characteristics of National Health Safety Network ventilator- associated events. Crit Care Med 2014;42:2019–2028.
8. Chang HC, Chen CM, Kung SC, Wang CM, Liu WL, Lai CC. Differences between novel and conventional surveillance paradigms of ventilator-associated pneumonia. Am J Infect Control 2015;43:113–136.
9. Klompas M. Potential strategies to prevent ventilator- associated events. Am J Respir Crit CareMed 2015;192:1420–1430.
10. Mann T, Ellworth J, Huda N, et al. Building and validating a computerized algorithm for surveillance of ventilator-associated events. Infect Control Hosp Epidemiol 2015;36:999–1003.
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80 |
Page 81 |
Page 82 |
Page 83 |
Page 84 |
Page 85 |
Page 86 |
Page 87 |
Page 88 |
Page 89 |
Page 90 |
Page 91 |
Page 92 |
Page 93 |
Page 94 |
Page 95 |
Page 96 |
Page 97 |
Page 98 |
Page 99 |
Page 100 |
Page 101 |
Page 102 |
Page 103 |
Page 104 |
Page 105 |
Page 106 |
Page 107 |
Page 108 |
Page 109 |
Page 110 |
Page 111 |
Page 112 |
Page 113 |
Page 114 |
Page 115 |
Page 116 |
Page 117 |
Page 118 |
Page 119 |
Page 120 |
Page 121 |
Page 122 |
Page 123 |
Page 124 |
Page 125 |
Page 126 |
Page 127 |
Page 128 |
Page 129 |
Page 130 |
Page 131 |
Page 132 |
Page 133 |
Page 134 |
Page 135 |
Page 136
