PEER-REVIEW | HAIR RESTORATION |
Figure 12 Density over 12 months using the base 100 model
125 120 115 110 105 100
occurred on the second day and disappeared spontaneously 2 days later.
M0 M3 M6 M9 M12 Regarding age, better results were recorded for
density after 60 years of age. (74%, against 33% between 40 and 60 and 25% under 40 years of age) (Figure 16). Again regarding stage, the authors could not
establish a correlation regarding the stage for men. For women, the authors clearly observed a correlation on stage 1: 15.35%, stage 2: 28.78%, and stage 3: 129.39% (Figure 17).
Diameter Globally, no significant changes were observed. However, focusing on women in stage 3, the authors observed a very positive evolution stage 1: -14%, stage 2: -1%, and stage 3: +36%. The authors looked to see if there
was a correlation between improvement and initial value. No statistically valid correlation with linear regression for either men or women was found.
Side-effects Pain is always present (from 2 to 5 on a 10 point scale). It is not a painless procedure and it could be useful to use analgesic gas. For one patient a preauricular lymph node
The authors
looked to see if there was a correlation between
improvement and initial value [on diameter]. No
statistically valid correlation with linear regression for either men or women was found.
32 ❚
Limit of this evaluation It is impossible to take measurements all over the scalp. Therefore, the authors had to choose an evaluative area to see the changes brought about by the procedure. Nevertheless, the results can be different between areas. For example, an 18% improvement was observed on the border line for a man in stage 5, while no changes were detected on the vertex area. Using adhesive also posed an issue. Before taking the
digital phototrichogram, the authors cut the hair very short and used an adhesive tissue to take away hair fragments in order to get a clear picture. The hypothesis cannot be excluded that some telogen hair was present in the area and was subsequently removed. The authors’ protocol used two therapeutic parameters: PRP and microneedling. Even if clinical experience shows that the most important effect is due to the PRP, this evaluation is unable to prove it. The goal was to get the best result for the patient and the authors are evaluating other studies with different protocols
(without
microneedling, with activation, and with less quantity) and will soon be able to quantify the result and
improve the protocol. The number of patients who dropped out of the study before the 12 month follow-up was high but this is not a prospective study, this is a retrospective
evaluation.
Conclusion In conclusion, the authors evaluated 70 cases of androgenic alopecia over a period of 3 months, and 46
Figure 13 (A) Before and (B) 12 months after two PRP sessions March 2015 |
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Density
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