| HAIR RESTORATION | PEER-REVIEW
■ Digital phototrichogram ■ A search for side-effects ■ Local anaesthesia, application of the dermaroller, and injection of PRP.
Examination on day 180, 270, and 360 ■ Photographs taken again from the same six angles ■ Digital phototrichogram ■ A search for side-effects.
Treatment with PRP and dermaroller First, a local anaesthesia injection of 1% lidocaine must be given prior to use of the dermaroller or intradermal injections of PRP. In order to allow better diffusion of the PRP, multiple
perforations were conducted on scalp areas affected by the process of androgenic alopecia using a single-use dermaroller instrument with peaks of 1.5 mm. Next, treatment with PRP involves the injection of 10 cc
of PRP obtained by centrifugation of the PRP kit with the centrifuge pre-programmed for this purpose. The injections will cover the area of the affected scalp. The preparation of the PRP was made in accordance with the operating instructions of the kit manufacturer.
Review of side effects Common side-effects associated with PRP injections and dermaroller include the following: ■ Pain ■ Redness ■ Pruritus ■ Oedema ■ Haematoma ■ Other.
Results at 3 months Density At day 90, the authors observed an improvement of 19.7% in hair density, which they believed to be a very interesting result coming 3 months after the first session. The patients reported no more hair loss after 2 or 3 weeks after their first session. However, an initial acceleration of the fall due to the telogen expulsion was observed in some patients. The repartition of the improvement was found to be
very close between terminal and vellus hair (terminal +30.8% and vellus +28.3%). Hairs are considered as vellus if the diameter is <40 microns. The percentage of improvement is defined as: (density
at 3 months minus initial density) divided by initial density. It is not the number of new hairs. Regarding sex, (Figure 5) the authors observed a small
advantage for the men in density variation (21.3% against 18.5% for the women).
Figure 5 Density and diameter variation at 3 months regarding sex
25.00 20.00 15.00
10.00 5.00 0.00 −5.00
F
Density var Caliber var
18.48 1.96
M
21.29 -1.82
Figure 6 Density and diameter variation at 3 months regarding age
35.00 30.00 25.00 20.00 15.00
10.00 5.00 0.00
−5.00 −10.00
Density var Caliber var
20–39 17.06 1.46
40–59 16.74 1.53
60–80
30.59 −4.57
Figure 7 Density and diameter variation at 3 months regarding stage
Stage men
40.00 30.00 20.00 10.00 0.00
−10.00 −20.00
2 3 4 5
Density var 12.96 28.04 21.60 22.72 Caliber var −11.43 0.87 0.77 −11.91
Stage women
30.00 25.00 20.00 15.00
10.00 5.00 0.00
−5.00 −10.00 1
Density var Caliber var
18.52 −5.31
2
16.88 2.05
3
25.33 10.05
6 7
13.22 24.45 17.65
4.54
At day 90, the authors observed an improvement of 19.7% in hair density, which they believed to be a very interesting result coming 3 months after the first session.
prime-journal.com | March 2015
❚
29
Variation
Variation
Variation
Variation
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80 |
Page 81 |
Page 82 |
Page 83 |
Page 84 |
Page 85 |
Page 86 |
Page 87 |
Page 88 |
Page 89 |
Page 90 |
Page 91 |
Page 92 |
Page 93 |
Page 94 |
Page 95 |
Page 96