PEER-REVIEW | HAIR RESTORATION |
correlation regarding the stage for men. For women, they clearly observe a correlation on stage (stage 1: -5.31%, stage 2: +2.05%, and stage 3: +10.05%).
Telogen/vellus ratio The results concerning the ratio are comparable with the diameter evolution. Over the 90 day period, the authors observed many
Figure 8 (A) digital image taken on day 1, and (B) at the same place on day 90 showing the change in hair density
differences as illustrated by the digital hair image in Figure 8. As can be observed in Figure 8, the two images were taken exactly in the same place. The highlighted area shows the variation in hair density, which is changing from 3 to 5, 0 to 1, 2 to 3, and 2 to 3. This is a very important result that confirms clearly the effect of PRP on density. The results can be seen in the macrophotographs before and 3 months after one PRP session (Figure 9).
Results at 12 months Following 12 months from the first treatment, only 46 patients (out of the initial 70) were still involved in the study due to several causes: ■ Distance (7): The PRP procedure is not often used,
At 12 months, after two sessions of
PRP, an improvement of 38% in density variation was observed. This is a very important evolution.
Figure 9 (A) Before, and (B) 3 months after one PRP session Regarding age, better results on density change were
witnessed in patients over the age of 60 (30.6% against 17% for those under 60 years of age) (Figure 6). Regarding stage, results were not as responsive for
men in stages II and VI of the Norwood-Hamilton scale (Figure 7). Statistically, a clear correlation cannot be established between the results and the stages of hair loss for men. On the other hand, the female group showed higher values on stage 3 (25.3%) vs stages 1 and 2 (17%).
Diameter At day 90, the mean diameter does not change (+0.3%). Regarding sex, the authors observe a little advantage for the women (+1.96% against -1.82% for the men). Regarding age, results are not so
positive on diameter after 60 years (-4%). It seems that there is a correlation between hair density and the growth of new thin hair, so the mean diameter decreases. Rega r d i ng the
stage,
authors could not establish a
30 ❚ March 2015 |
prime-journal.com
so recruitment is not local but rather national or international. This explains the monitoring difficulties
■ Pain (2): This is not a painless procedure and pain evaluation is between 2 and 5 on a 10 point scale
■ Loss of tattoo (1): Despite a standardised technique, sometimes the skin does not keep the pigment.
■ Not enough of a result and the patient did not return (4) ■ Unknown (10).
Density At 12 months, after two sessions of PRP, an improvement of 38% in density variation (Figure 10) was observed. This is a very important evolution. For most of the patients, the improvement was observed at about 6–8 months. Another way to evaluate the evolution is to
observe the density in absolute value (Figure 11). The initial mean was 128 hairs/cm² and it increased to 161/cm² at 12months. However, the more accurate way is to evaluate the result is by using base 100 (Figure 12). This formula is often used in financial statistics to evaluate the yield of an investment. Values
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