PRIME PEOPLE | NOEL THOMAS PATTON |
NOEL THOMAS PATTON T.A. SCIENCES
Balraj Juttla discusses the development of telomerase activation
technology with Noel Patton, Founder of T.A. Sciences, and how the science behind it is opening up a new side to anti-ageing medicine
A 96 ❚
NTI-AGEING MEDICINE has long been about making the body look younger, but what about making the body biologically younger?
Too good to be true? Well, thanks to years of research into telomeres and telomerase activation, it could now be a possibility. At the forefront of this technology is
Noel Patton, Founder of T.A. Sciences and one of the technology's biggest advocates. Noel is happy to explain how the complex science works and the role he and T.A. Sciences have played in bringing a unique anti-ageing product to market.
Telomeres It begins with telomeres,
stretches of
DNA that sit at the ends of each of the 46 chromosomes present in every cell. Chromosomes are linear pieces of DNA and the telomeres sit at either end, making 92 telomeres present in each cell. Noel describes them as being like the plastic tips on the ends of shoelaces, preventing the chromosomes becoming
damaged. Each time a cell divides, the chromosomes are duplicated in order for the same genetic information to be passed to every new cell. During this process, telomeres lose base pairs of DNA and become shorter. This shortening of telomeres continues each time the cell divides, a process that occurs throughout a person's life. Telomeres can be seen as an ageing clock, the shorter the telomeres, the older the cell. When a few telomeres become too short, a cell can no longer divide and the cell reaches replicative senescence, which can then result in the onset of various conditions associated with old age. Research suggests that the shortening
of telomeres is a risk factor for diseases such as COPD, macular degeneration, and pulmonary fibrosis, as well as being directly related to cells reaching the Hayflick Limit (i.e. the total number of times a cell can replicate). If scientists could find a way
to prevent the
shortening of telomeres, they could slow down the onset of old age and its associated conditions.
March 2013 |
prime-journal.com Noel explains there are only two
known ways to slow down the shortening of telomeres; the first is to follow a healthy lifestyle: to exercise, cut down on alcohol, and eat a healthy diet. The second thing would be to take a product that directly activates telomerase.
Telomerase Activation 'Telomeres are like a burning fuse, the fuse is lit at conception and keeps burning down your whole life, but if you can lengthen the fuse, the explosion will be postponed. In this case, the explosion is when the cell reaches a crisis, becomes senescent, or sends itself into apoptosis and dies.' Noel tells me this 'lengthening' can be
achieved through telomerase activation. Telomerase is an enzyme produced in cells and, when activated, can add base pairs of DNA back onto telomeres, making them longer again. This is important as the longer the telomere, the more the cell can divide before it reaches senescence and dies. Increasing the number of times a cell can divide is not the only benefit of
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