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| FACIAL AESTHETICS | PEER-REVIEW The initial part of LED irradiation, consisting of CW


light emission, could have been associated with a photobiochemical and moderately photothermal ‘priming’ of exposed cells, preparing the ground for a better response to the on–off biostimulatory effect induced by PW irradiation during the final part of the treatment. The idea of evenly distributing LED arrays along the inner surface of an anatomically designed polystyrene facial mask has shown to be quite effective in keeping light delivery distance as short and constant as possible (8 mm ± 4 mm), all along the complex surface anatomy of facial skin. This particular innovative feature could have been responsible for a consistent optimisation of facial irradiance and consequently, for the overall photobiological effectiveness of this treatment. Small sample size and full-face treatment represent


two study limitations, but split-face studies are already planned to further prove the efficacy of this interesting non-invasive skin rejuvenation protcol.


Conclusion Predominantly non-thermal high-energy LED photobiomodulation performed with an innovative facial mask light delivery system using a sequential combination of 840 nm CW and 880 nm PW irradiation has proven effective in positively modifying skin tone and texture of prematurely aged facial skin. Clinical results were confirmed by objective and subjective assessment 15 and 45 days after completion of full treatment sessions. Textural, wrinkle, and skin elasticity modifications were found more pronounced 15 days after the end of the eight LED treatments and showed a slight decrease after 45 days, thus indicating the need for a periodical repetition to keep tissue functional improvements. Sequential combined narrow-band CW + PW LED treatment was reported to be painless, safe, and easy to perform.


References


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prime-journal.com | March 2013 ❚ SKIN TONE


100% 80% 60% 40% 20% 0%


30% 50%


20% 20%


40% 30% 10% T2 (T1+45) Extremely effective T3 (T1+75) Very effective Effective


100% 80% 60% 40% 20% 0%


SKIN COLOUR UNIFORMITY 30%


20% 10% 20%


20% T2 (T1+45) Moderately effective


30% 10%


30%


20% 10%


T3 (T1+75) Totally ineffective


Figure 14 Subjective perception of LED treatment efficacy on overall skin tone improvement and skin colour uniformity at T2 = T1 + 45 days, and T3 = T1 + 75 days as reported by study subjects


The combination of such visible and consistent


aesthetic improvement and the feasibility of the treatment sessions led all study subjects, in the end, to agree in recommending an anti-ageing treatment with EPI-C Plus 840–880 nm LED facial mask. The innovative LED array distribution on the inner aspect of an anatomically designed facial mask positively contributed to the consistency of clinical results owing to the almost constant minimal distance between light sources and facial skin surfaces. More studies are needed to identify maintenance treatment intervals to keep clinical results within an acceptable range, aiming at an effective, long-lasting ‘healty ageing’ protocol.


Declaration of interest Loan of equipment for research


purposes Figure images © Dr Leonardo Marini


Key points


n Predominantly non-thermal high-energy LED photobiomodulation has proven effective in positively modifying skin tone and texture of prematurely aged facial skin


n Sequential combined narrow band CW + PW LED treatment was reported to be painless, safe and easy to perform


n The innovative LED array distribution on the inner aspect of an anatomically designed facial mask positively contributed to the consistency of clinical results


39


% of subjects


% of subjects


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