PEER-REVIEW | FACIAL AESTHETICS |
Figure 4 Computerised facial complexion analysis (wrinkles) at T0 (immediately
pre-treatment (A)) and T45 (15 days after eight LED treatments (B))
All ten subjects
completed the full series of treatment
sessions and attended all scheduled follow-up visits.
the face, thus leading to an important bias in this kind of pilot study.
Treatment All subjects were asked to temporarily suspend routinely applied topical facial products 15 days prior to initiation of treatment. A standardised skincare regimen was prescribed during the 15-day pre-treatment ‘wash-out period’ according to the following: ■ Ictyane cleansing cream (Ducray Laboratoires Dermatologique, Pierre Fabre, France) — one application twice daily
■ Thermal spring water mist (Avéne, Pierre Fabre, France) — one mist twice daily immediately before moisturising cream
■ Ictyane moisturising cream (Ducray Laboratoires Dermatologique, Pierre Fabre, France) — one application twice daily immediately after Thermal spring water
■ Anthelios SPF 50+ cream (La Roche Posay Laboratoires Dermatologique, France) — one application every morning on top of moisturising cream, to be repeated every 2 hours in cases of prolonged UV exposure. The same skincare regimen was maintained for the
duration of LED treatment, and represents a standard hydrating protocol with creams with hydrating properties and none with anti-ageing properties. This standardisation was introduced to avoid any bias from other anti-ageing creams eventually applied subjectively at home.
Figure 5 Skin texture digital features count variations
(standardised L + R cheek Visia complexion analysis
measurements — median values) and corresponding
percentages of global texture improvement (L + R
cheek — median values) at
T1 = baseline, T2 = 15 days, and T3 = 45 days post-treatment
1280 1240 1200 1160 1120 1080
28 ❚
WRINKLE REDUCTION 1269.93
1188.30 1156.10
All patients received eight full-face LED treatments
over a 1-month period. Two treatments were scheduled per week, with a minimal interval of 3 days between treatments. All patients were instructed not to wear any facial make-up from the night prior to treatment. Gentle facial cleansing with Ictyane cleansing cream was performed immediately pre-LED light exposure. Cleanser was rinsed off with lukewarm water. The LED facial mask was carefully positioned on facial skin and retaining straps were adjusted to obtain a perfect anatomical match between LED array and facial skin, keeping light source distance to an average of 5 mm (8±4 mm). Each treatment consisted of standardised 15 minute pre-set 835±5 nm CW LED (50%) plus 15 minute pre-set 875±5 nm PW LED (50%) exposures for a total irradiation dose of 66 J/cm2 (33 J/cm2
per session + 33 J/cm2 ). Immediately post-treatment, Thermal spring water
mist followed by Ictyane moisturising cream were applied to treated skin. All subjects were instructed to wear daily high SPF sunscreen, and minimise sun exposure. Make-up was allowed 1 hour after treatment.
Clinical photographs Standardised clinical photographs were taken at baseline, immediately before the first LED exposure (T1), at 15 days (T2 - T1 + 45 days), and 45 days (T3 - T1 + 75 days) after completion of eight treatment sessions using a 10.5 megapixel EOS 1000D digital camera (Canon Inc, Tokyo, Japan), a EF-50 mm f/2.5 Compact-Macro lens (Canon Inc.), and a 220EX Speedlite dedicated TTL flash
0% -2% -4% -6% -8%
-10% T1 T2 T3 T1 T2 T3
GLOBAL TEXTURE IMPROVEMENT % 0%
-6.43% -8.96%
March 2013 |
prime-journal.com
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