Company insight
Devices making closed- loop applications a reality
CorTec provides novel implantable technology to overcome current limitations: With its Brain Interchange Implant, CorTec enables researchers, medical institutions and industry to investigate new therapies; furthermore it develops components and subassemblies for Medical Devices.
lectrical brain stimulation has been clinically used since the 1990s to treat neurological diseases. Most companies in the field of medical device development are unwilling to take device development risks and therefore rely on established components and technologies, limiting new therapy developments. However, research on electrical stimulation has increased in recent decades. With new findings, novel treatment options might become a reality in the course of the next decade. What still limits the innovation in neurotechnology, is the lack of devices that meet the specific needs of researchers and physicians. CorTec is developing the Brain Interchange Platform Technology that enables researchers, physicians and the rest of industry to develop new therapies based on new research findings.
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How the Brain Interchange works The Brain Interchange system can be used in a range of device designs, in scientific studies and as components of complete therapeutic systems. The low-latency system allows open and closed-loop interaction with the nervous system, enables data processing outside the body and tailored brain stimulation as response to biological signals. The active implantable system can continuously monitor the patient’s physiological condition and readjust the applied electrical stimulation based on the evaluated data according to the patient’s individual therapeutic needs at any given point in time.
The Brain Interchange system consists of three components. First is the implantable unit. Multi-contact °AirRay grid electrodes are connected to the functional core and the electronics – which are protected by the proprietary hermetic ceramic encapsulation. The electrodes are typically placed on the brain’s surface as the direct interface to the
Evaluation Kit of the Brain Interchange System, comprising all components in a bench-top version. components are not limited to
nervous system. The electronics amplify, filter, digitise and stream neural signals to the external unit, as well as modulating the brain activity by applying electrical pulses via the grid electrodes. Second is the external unit. This component wirelessly powers the implantable unit using an inductive coil and wirelessly communicates with the it via a proprietary 2.4 GHz protocol. Finally, there is the processing unit. The external computer that powers the external unit and communicates with it via USB. It runs algorithms for processing the stream of recorded neural data and initiates stimulation commands with low latency.
From an idea to a device All components of the Brain Interchange System are available for medical device development in industry and research. With over ten years of experience, CorTec is providing solutions that are suitable for pre- clinical and clinical applications. Although, CorTec’s Brain Interchange System has been developed for the treatment of neurological diseases, the technology spectrum and
Medical Device Developments /
www.nsmedicaldevices.com
neurotechnology and can be adapted to the individual requirements of the application. These components are: ■ A high-channel ceramic implant housing technology providing 100 or more electrical feedthroughs.
■ A voidless silicone overmolding for the protection of electronics.
■ °AirRay electrodes for interfacing with the peripheral and central nervous system. They offer a combination of flexibility, softness, stretchability, thinness, and contact density.
■ The electromechanical interconnection technology for active implants.
CorTec provides all needed solutions for future therapies. Its services include all important steps to realise the idea of a product. With application related, technological and regulatory expertise CorTec supports every single step on the way to an individual medical device. ●
www.cortec-neuro.com 91
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