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Company insight


wire forming, micro-tubes, component manufacturing and plating capabilities to our medical offering. We also added a new geographic footprint which has increased our ability to support customers in EMEA. Since 31 August Polyfil is renamed Alleima Zug and Galvarex Alleima St Imier.


Can you explain how Alleima’s wire solutions are used in highly accurate sensors for remote monitoring devices? The primary purpose of Alleima’s medical wire solutions branded Exera is to be an active – and in many cases the lead – part of whatever medical device they are in. The wires are used to stimulate or send some sort of signal either inside or outside the body. In almost all cases, the wire is an active part of how the sensor works – a continuous glucose monitor wire, for example, is an active chemical sensor for sensing the amount of blood sugar in your interstitial tissue. Most of these are used in Type 1 diabetes cases. As you can imagine – for younger children especially – the parents’ anxiety about whether their child’s glucose and insulin levels are right can be quite intense. But the wire-sensor put into the patient constantly monitors when outside intervention is necessary. Because a parent can’t always be with their children, you can imagine the relief they feel when they can actually look on their smartphone and see what’s happening


with their child who may be miles away at school or a friend’s house The Exera sensor solutions have also been used in composite wire that incorporates different elements into a single system. One part of the wire is used to locate the sensing device inside the body, almost like a smart guidewire. Another senses heat, while another senses glucose levels in the blood in a CGM, or it senses blood flow and pressure in the device that will prevent and manage heart failure before it gets to an acute stage.


What part do Alleima’s products play in early detection solutions for diseases such as cancer? There’s a new device we’re getting involved with bringing to the marketplace that will prevent and manage heart failure before it gets to an acute stage. The wire is inserted in your cardiovascular system and there’s an antenna attached to this sensor – so the whole system provides a continuous output of blood flow and pressure that gives the physician an indication that you’re starting on the early stages of heart failure and pinpoints exactly where the problem areas are.


The physician can then start you on a remedial path long before your condition can be considered acute. A clinician can look at a patient’s history, heritage, body type or other aspects and offer the service to patients who might be at risk. It enables them to


prevent medical issues arising before it’s too late.


Another area in which our Exera ultra- fine wire is used is in locating breast tumours, enabling early detection of a disease that kills hundreds of thousands of women every year. As well as supporting early detection of breast cancer, this wire localisation method results in less breast tissue removal and keeps scarring to a minimum – contributing to the psychological well- being of the patient.


In cardiology, fine wires are needed in procedures such as cardiac catheterisation and pacemaker leads. What are the qualities that make Alleima’s fine wires so suitable for these procedures?


Alleima uses alloy and coating materials that are highly stable in the body, processing those materials in such a way as to reduce as far as possible the problems from known and well- understood failure points. In particular, our materials are designed to minimise the risk of cyclical fatigue.


Cyclical fatigue normally occurs as a consequence of three factors, where Alleima is outstanding: cleanliness of the melt, specialised surface treatment and drawing die quality. Our very long history of more than 160 years in materials development and in-house die manufacturing is key, and we have drawn on our experience in other demanding industries and transferred it to the production of precision medical wire where the material must last a lifetime. It must be tested over and over again to ensure it will never fail.


In our commitment to the needs of our customers, we systematically collect data about the new and growing challenges facing them. Our engineers and specialists work closely with customers to jointly discover ways of addressing these challenges with new or modified products. Alleima engineers have the right combination of academic qualifications and hands-on experience – and enjoy an active international exchange programme with leading research centres and universities worldwide. ●


Alleima keeps control over the supply chain, from R&D to melt to the final fine wire products. Medical Device Developments / www.nsmedicaldevices.com www.alleima.com/exera 117


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