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COVER STORY: MIBELLE BIOCHEMISTRY ADVERTISEMENT FEATURE PinoPlexTM


Beautiful, healthy-looking hair is characterized by an optimal moisture balance. Physical and chemical stress can damage the hair cuticles, causing them to protrude and act like an open door which leads to moisture loss. It is therefore crucial to restore and retain moisture in the damaged hair fibres. Based on a bio-inspired concept, PinoPlex™


is an upcycling hair active that delivers excellent moisture, which not only penetrates the hair but is also successfully trapped inside by the smoothing of the cuticles. This makes the hair shinier and more resistant to daily stress.


Moisture is the base for beautiful hair PinoPlex™ was tested for its moisturizing effect on damaged hair. Compared to the untreated control, PinoPlex™ significantly increased the weight and thus the moisture content of the hair. Low-field nuclear magnetic resonance (LF- NMR) spectroscopy confirmed that PinoPlex™ increased water absorption into the damaged hair fibre and locks-in the moisture (Figure 1). After daily application of PinoPlex™, a


significant improvement in hair shine was observed. In tests performed on damaged hair to evaluate prevention of split ends, PinoPlex™ was able to reduce the formation of split ends by 25% compared to placebo. Atomic force microscopy (AFM) imaging


demonstrated that PinoPlex™ smooths hair cuticles (Figure 2). This was evident by a significant reduction in measured cuticle height, demonstrating the efficacy of PinoPlex™. By smoothing the scales, PinoPlex™ protects the integrity of the hair fibre, locks in moisture and improves the external appearance of the hair by making it shinier.


Increase in hair resilience An increased elastic modulus means higher resistance of the hair, as more force is required to deform or break it. To investigate this, a hair fibre treated with PinoPlex™ was analyzed using AFM and compared with an untreated control.


12 9 6 3 0


Placebo ■ 1% PinoPlex™ ■ *


* *p<0.05 versus control Figure 1: Increase in moisture content (LF-NMR) www.personalcaremagazine.com Figure 2: Smoothing of hair cuticles


Bolimattstrasse 1 5033 Buchs Switzerland www.mibellebiochemistry.com info@mibellebiochemistry.com


July 2024 PERSONAL CARE July 2024


7 hair moisturizer INGREDIENTS ● FORMULATION ● : the bio-inspired PERSONAL CARE


MANUFACTURE GLOBAL


Wet Dry Healthy these cells. In addition, PinoPlexTM Damaged effectively


counteracted internal and external stressors that lead to oxidative stress and negatively affect hair growth and appearance by increasing protective genes and reducing inflammatory markers.


A bio-inspired upcycling concept from pine cones PinoPlexTM


Interview: The K Beauty Science’s Jayanne Jin


In focus: Anti-pollution Functionals Testing


Results showed that treatment with PinoPlex™ strengthens the hair fibre by increasing its elastic modulus. In other words, when treated with PinoPlex™,


the hair fibre can withstand more styling and environmental stress before hair breakage occurs. This not only strengthens the health of the hair, but also gives it a vibrant bounce.


Supporting keratinocyte differentiation for healthy hair Since strong hair starts at the root, an active ingredient beneficial for the hair shaft should also have positive effects on the root. Keratinocytes in the hair root are the most important cells for the hair, as fully differentiated keratinocytes are the basis for the formation and growth of hair fibres. Gene expression analysis revealed a positive


effect of PinoPlex™ on the keratinocytes which indicates a beneficial effect on the hair root. The active exhibited pro-differentiating effects on


Control 1% PinoPlexTM (INCI: Pinus Sylvestris Cone Extract


(and) Glycerin (and) Sodium Benzoate (and) Aqua/Water) is based on an extract from the cones of Scots pines. The cones are collected in sustainably managed French forests and are considered a waste product after the extraction of the seeds. The pine cones are used by Mibelle


Biochemistry as upcycled material for the production of PinoPlexTM


. But what is the


connection between pine cones and hair? Pine cones exhibit a fascinating phenomenon when they are immersed in water: their scales close after a short time. This is reminiscent of hair scales: well-


moisturized hair has closed cuticles, while dry, brittle hair has open cuticles! Thus, the pine cone served as a bio-inspirational model for the development of PinoPlexTM


. To obtain the valuable ingredients, the pine


cones are subjected to a gentle, microwave- assisted extraction process specially developed for the hard, woody material. The resulting extract contains numerous valuable ingredients such as osmolytes. These molecules contribute to the regulation and optimal water balance and are known to have a moisturizing effect on the hair, protecting it from drying out. Therefore, PinoPlex™ serves as a powerful


moisturizer for the hair, which has a beautifying and strengthening effect on the hair shaft, but also supports hair growth by positively influencing the hair follicle.


PC


한국인 언어 부분 을더한:


compared to untreated control %


Total amounts of protons


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