37 Pumps, Valves & Liquid Handling Flow Device Helps Improve Accuracy and Reproducibility of Chemical Reactions
For labs looking to improve accuracy, reproducibility, and yield from liquid phase chemical reactions, Testa Analytical Solutions eK has developed the Chemistry flowmeter.
Accurately measuring the rate of addition of liquid reagents is a critical consideration for many labs undertaking batch or flow chemistry reactions. When using peristaltic or piston pumps to add expensive chemicals or other fluids into a reaction, labs must ensure the rate of addition is both accurate and constant as part of quality control. Without accurate flow measurement, too much or too little chemical can be injected into a reaction. Also, if the rate of addition of reagents is not constant this can also result in adverse outcomes, expensive reagent overuse, lower final product yield and safety issues. In fact, inaccurate flow measurement can mean the difference between profits and lost revenue.
Designed to be fully compatible with most solvents, acids, and bases, the Chemistry flowmeter sets a new standard for continuous, non-invasive measurement of the flow rate of pumps being used to add liquid reagents to chemical reactions. Compact in size, and conveniently powered via a USB connection, the Testa Analytical Chemistry flowmeter uses a thermal flow sensor that is extremely accurate, sensitive, and high-resolution. As the sensor is non-invasive it can operate over a wide dynamic range and has been demonstrated to be the perfect real-time flow measurement tool for monitoring both batch and flow chemistry reagent addition pumps.
The Chemistry flowmeter uses a highly intuitive PC-based app for continuous recording, display and storage of the measured flow rates. The current reagent addition flow rate is also displayed on the devices integral high-resolution OLED Display, ensuring the accuracy and consistency of reagent addition is readily controlled.
More information online:
ilmt.co/PL/L2GZ 59206pr@reply-direct.com
Versatile Pipettes Selected for Prestigious International Competition
Students of Technische Universität Braunschweig, Germany, used Integra Biosciences’ VIAFLO electronic pipettes and EVOLVE manual pipettes to perform sample transfers and dilutions as part of their project for the 2022 iGEM competition. The pipettes helped the team to speed up liquid handling and increase pipetting accuracy, giving the students a competitive edge over their peers.
The iGEM Foundation is an independent, non-profit organisation dedicated to the advancement of all areas of synthetic biology. It runs an annual international competition where multidisciplinary teams of university students design, build and test their own unique research projects from start to finish. The group at Technische Universität Braunschweig (TU_BS) developed a self-amplifying detection system for the competition, which can be used to identify small amounts of tumour marker antigens in blood samples. This novel tool has the potential to contribute to the early diagnosis and treatment of many cancers, improving patient outcomes and survival rates in the long term.
Benjamin Harder, a student at TU_BS, explained: “We were the first iGEM team at our university for some time so, until recently, we had only a few outdated pipettes available to us. We therefore decided to upgrade to I Integra’s VIAFLO electronic pipettes and EVOLVE manual pipettes. They are well suited to our applications, as they allow us to rapidly adjust the dispensing volume on the fly, making our liquid handling steps faster and more efficient than before, while simultaneously minimising manual errors and reagent wastage. This noticeably improved the accuracy and reproducibility of our results, giving us greater confidence in our findings.”
“Every day working on our project in the lab was different and unpredictable, but I Integra’s products greatly helped us to deal with some of the surprises and challenges we came across as we got closer to the final of the exciting competition,” Benjamin concluded. All teams presented their cutting-edge projects during the iGEM Grand Jamboree in Paris, France, from the 26th to the 28th of October 2022, with prize winners being announced on the final day. TU_BS was awarded a silver medal for their innovative project, a much-deserved reward for the group’s months of hard work.
More information online:
ilmt.co/PL/Z4v9 and
ilmt.co/PL/QqGX 59583pr@reply-direct.com
Bottle-top Dispensers Deliver Safety in Chemical Handling
The Calibrex™ bottle-top dispensers from Socorex are robust precision instruments intended for a safe and reproducible liquid distribution. Directly screwed on the reagent bottle, they limit possible eye or skin contact, or vapours inhalation. The line covers 7 volume ranges: 0.1-1 / 0.25-2.5 / 0.5-5 / 1-10 / 2.5-25 / 5-50 / 10-100 mL. Select the most appropriate model, according to the type of liquid distributed:
Calibrex™ organo 525 includes a ground glass or ceramic plunger, both well suited for organic solvents and non-crystallising solutions.
Calibrex™ solutae 530 has a PFA coated glass or ceramic plunger for trouble free distribution of salt solutions, weak and strong acids and bases.
To easily check chemical compatibility of Calibrex™ dispensers, a QR code printed on each instrument body gives instant access to the resistance chart. Valves, plunger, barrel, and delivery jet are removable in seconds for cleaning or replacement. If required for instance in microbiology or cell culture laboratories, Calibrex™ dispensers are fully autoclavable at 121°C.
The optional fl ow control stopcock increases Calibrex™ dispenser safety by recycling reagent directly into the bottle while priming. Other accessories extend working possibilities, such as a 60 cm fl exible extension tubing. It allows easy distribution in tube rows. This is very convenient when preparing dilution series.
A dispenser screwed on a small bottle may lack stability. The use of a holder increases stability and eliminates risk of instrument tipping. When different bottles sizes are used with the same dispenser, the telescopic feed tubing is recommended to instantly fi t to any bottle size.
More information online:
ilmt.co/PL/X2XL and
ilmt.co/PL/9xBy 58249pr@reply-direct.com
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76 |
Page 77 |
Page 78 |
Page 79 |
Page 80
