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35 New Benchtop Evaporator Removes Even Highest Boiling Point Solvents


Genevac has launched the EZ-2 Elite - a new addition to its popular EZ-2 evaporator range. The EZ-2 Elite is designed to remove high boiling point solvents and deliver enhanced solvent recovery thereby improving final drying of stubborn samples and enabling fast lyophilisation of HPLC fractions. The high performance scroll pump used with the EZ-2 Elite delivers deeper vacuum than the diaphragm pumps used on other EZ-2 systems. This advance plus internal enhancements to heat vapour duct and system components enable the EZ-2 Elite to routinely evaporate challenging high boiling solvents including DMSO and NMP. In addition these enhancements ensure that such challenging solvents only condense in the SpeedTrap, and not anywhere else.


The SpeedTrap™ on the EZ-2 Elite works just like the other EZ-2 models but with the added benefit of automatic defrost and drain technology. The EZ-2 controls the SpeedTrap and the new Elite solvent collection vessel to allow mid-method defrosting and draining. This controlled draining facility enables very high levels of solvent recovery to be achieved. For example, when working with HPLC fractions, higher levels of dryness can be achieved by first draining the volatile organic solvent before tackling the water, allowing full vacuum to be used during final drying. Using the EZ-2 Elite SpeedTrap - the Genevac LyoSpeed™ method of fast lyophilisation of HPLC fractions is possible for the first time on an EZ-2 Evaporator.


Running the EZ-2 Elite is as simple as 1, 2, 3. Just load samples, select maximum safe temperature for samples, select solvent type and hit start. Offering true unattended operation capability the EZ-2 Elite requires no user training, even a beginner can competently use the system within 5 minutes. The EZ-2 Elite has been designed to concentrate or completely dry samples. The system will accommodate a wide selection of sample holders enabling evaporation from most common sample container formats including round-bottom flasks up to 500ml, tubes up to 160mm long, custom reaction blocks and shallow or deep-well microplates. To meet the need of the many life science companies switching their compound generation programmes from serial chemistry to parallel synthesis, the EZ-2 Elite is also able to take tubes, flasks and vials directly from the synthesis process, eliminating a manual handling step, increasing recoveries and removing the chance of cross contamination.


Circle no. 131 Highly Sensitive and Specific Chromatin Immunoprecipitation (ChIP) Assay Kit


Porvair Filtration Group has developed a new technology that has particular relevance to the rapidly expanding Epigenetics market and will be unveiling it at the Epigenetics World Congress in Boston in April 2011.


Chromatin Immunoprecipitation (ChIP) is the key experimental technique used to investigate the interaction between proteins and DNA in the cell. It aims to determine whether specific proteins are associated with specific genomic regions. ChIP is a core enabling technique that is being widely adopted in the rapidly growing field of Epigenetics.


Using a new approach, based on a rigid porous polymer matrix rather than the traditional sepharose or magnetic beads, Porvair has developed a novel Chromatin ImmunoPrecipitation (ChIP) assay kit called Chromatrap™.


Results from third party field trials, to be presented at the Epigenetics World Congress, demonstrate that Chromatrap™ is able to routinely deliver greater ChIP specificity, higher ChIP sensitivity and faster separations than traditional sepharose or magnetic bead approaches.


Circle no. 132


ADVERTORIAL SCHOTT®


Instruments UviLine 9100/9400 Photometers: Accessories for Special Applications Automatic Cell Changer 5+1


The SCHOTT®


Designed to analyse 5 samples and 1 blank, this accessory guarantees automatic applications with stable measurements and unique advantages.


• Removable and easy-to-reinsert turret for convenient cells setup


• Accurate positioning of low volume cells


• The blank value is always read before the sample measurement – a clear advantage for kinetics measurements.


Instruments UviLine’s large cell


compartment allows the use of a large range of accessories to extend the spectrophotometer’s application range and to automate the workflow.


The ‘QuickLock’ system allows to exchange all accessories easily with a press of the finger.


All automatic accessories such as automatic cell changer, sipper or thermostated cell holder are fully software driven.


Cell Holders


A single cell holder for up to 10 mm optical path length is included in the standard delivery of the UviLine. It can be used with micro cells up to 50 µl. An optional water thermostatable version is also available. A single cell holder for up to 100mm optical path length can be used instead.


Sipper


The sipper makes operation safer and increases productivity. It comes with a peristaltic pump integrated in the cell holder which is water thermostatable and allows programmable suction from 500 µl to 3000 µl and the use of flow-through cells from 30 µl to 450 µl.


Peltier Thermostatable Holder


The thermoelectric Peltier element either heats or cools down the sample in the cell to the required temperature. It is ideal for kinetic measurements.


• Temperature setup between 10°C and 60°C • Accuracy: ± 0.5°C • No external thermostat needed • Sipper option • Fast, ultra-compact and fully instrument driven.


Circle no. 133 Circle no. 134


INTERNATIONAL LABMATE - MARCH 2011 - LABORATORY PRODUCTS


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