9
Unique C18 Bonded HPLC Column
Chromatography Problems Solved by Reaching for the Sky
Many chromatographic problems, such as poor response and missing or tailing peaks are caused by activity in the inlet liner. These effects complicate quantification and can be particularly problematic for sensitive analytes. New Sky™ inlet liners from Restek are extremely inert, assuring complete transfer of analytes to the column, good response, and highly symmetric peaks. The exceptional inertness of these liners is due to a state-of-the-art deactivation process that broadly passivates the liner and packing so that they are inert to a wide variety of reactive analytes.
Some deactivations, such as base deactivation, are effective only for particular target compound chemistries. In contrast, the balanced deactivation of Sky™ liners prevents interactions with many chemical classes. Technical comparisons demonstrating the exceptional inertness of Sky™ liners toward complex pesticide probes, as well as to both acidic and basic compounds are available on Restek’s website. The comprehensive deactivation used for Sky™ inlet liners results in improved sensitivity, accuracy, and reproducibility, which allows analysts to quantify challenging compounds at trace levels with confidence, even when using wool.
Circle no. 25
ACEâ C18-PFP is a unique C18 bonded HPLC column from Advanced Chromatography Technologies, which has been developed to provide alternate selectivity to all existing C18 bonded phases.
The phase combines the hydrophobic characteristics of a C18 phase with the alternate selectivity offered by a pentafluorophenyl (PFP) phase – enabling the benefits of multiple interactions to be fully exploited. The phase also exhibits ultra low bleed to ensure LC/MS compatibility and demonstrates excellent temperature and pH stability.
At launch, materials are available in 3µm, 5µm and 10µm particle sizes and a full range of column dimensions from high throughput through to preparative scale.
Circle no. 26
New Column Formats for Faster and High Resolution Separations
Dionex is pleased to announce the release of three new MAbPac™ SCX-10 column formats for faster MAb analysis, pH gradients, and LC/MS use. The MAbPac SCX-10 is designed specifically for high-resolution analysis and characterisation of MAb variants.
The new formats include: 4 × 150mm for fast MAb separations; 4 × 50mm column for pH gradients; and 2 × 150mm for upstream separations in LC/MS applications.
The MAbPac SCX-10 column’s unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants with high resolution. Hydrophobic interactions with the resin are essentially eliminated resulting in highly resolved peaks.
The column, complementing the MAb Characterisation platforms, is designed to address the regulatory requirements for biopharmaceutical characterisation, providing unmatched column-to-column and lot-to-lot reproducibility.
Circle no. 27 ADVERTORIAL Whisper Nitrogen Generator
The Whisper Nitrogen Generator has been developed using the membrane technology to meet the specific requirements in terms of flow, purity and pressure in LC-MS applications. It can also be used for the evaporation of solvents in samples being analysed.
The model exists in different flow rates, with or without internal compressor. A specific Model called Whisper Hybrid has been specially designed for ABI LC-MS applications.
Circle no. 28 Hydrogen Generators
LNI Schmidlin SA has developed different type of Hydrogen Generators: The Classic line NM-H2-series is ATEX certified and has capabilities for cascading. The New Tech line H2-FID and H2-Carrier has a Touch pad display and an innovative water management system.
Both models employ’s the newest membrane technology available and includes the exclusive no maintenance auto drying technology. The pure gas (99.9999%) is ideal for operation with gas analysers, as fuel gas for flame tools, all kind of carrier Gas application, like GC and GC-MS (Mass Spectrometry), and as safe source of pure hydrogen in plasma chambers and other isolated environments.
Circle no. 29 LAB Air Stations
LAB Air Stations are available in 3 versions: AIR STATION: includes a quite built-in air compressor for to supply oil free and dry air.
ZERO AIR /ZERO AIR STATION: includes (for the STATION) a built-in compressor for to supply oil free and dry air. A catalytic oven removes the hydrocarbons down to 0.1 ppm
ULTRA ZERO AIR / ULTRA ZERO AIR STATION: includes (for the STATION) a built-in compressor for to supply oil free and dry air. A catalytic oven removes the hydrocarbons down to 0.1 ppm and in
addition a set of specific PSA filters to remove the CO2, CO, HC, NOX, SO2 and O3 contaminants and moisture down to 0.1 ppm.
Typical flow rates for the instruments are from 3L/min to 30 L/min. The uses of the LAB AIR STATIONS reduce the operating costs significantly.
Circle no. 30 H2-AIR FID Station
The LNI Schmidlin SA hydrogen generator is the economical answer to high-pressure gas cylinders in the laboratories.
Hydrogen and Air are generated from the same unit, ready to feed any kind of Flame Ionisation Detectors (FID). Zero Air is made from compressed Air from the laboratory and Hydrogen is made by electrolysis from the deionised water. The FID station is very small in food print and easy to operate.
Circle no. 31 Circle no. 32
INTERNATIONAL LABMATE - MARCH 2011 - CHROMATOGRAPHY
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