COMPANY PROFILE Lipotrue
LipoTrue acts as a central R&D engine integrating cutting edge technology platforms in order to innovate and swiftly adapt in the dynamic and fast-changing cosmetic market. Use of Wild Plants as Biofactories for human synthetic proteins synthesis, Big Data Analytics, in silico and biomimetic design of new peptides, Marine bio-research are high-tech platforms that LipoTrue manages for the rapid generation of the next active ingredients.
WISEGRADE™, EMBRACE THE WISE GRADIENT
The appearance of gray hair is based on the loss of pigmentation due to melanogenesis but can be also caused by emotional stress among others. Wisegrade™ is a plant-GMCSF that activates MITF pathways inducing endogenous antioxidants rebalancing redox homeostasis, protecting the stem cell pool, reactivating the melanosome cycle and reinforcing melanosome integrity. Wisegrade™ provides antioxidant protection, enhances gloss and allows to regulate the amount of grey hair in a natural non-damaging way.
V-4S™, FEELING TOTALLY SECURE
As part of a community humans want to feel safe and confident, but projecting an image of a radicalized skin could damage their self-image and cause them to lose confidence and self-esteem. V-4s ™ was born as the solution to recover the health of our skin by deeply protecting it from the four main radicals that cause a radicalized skin (wrinkles, redness, itchiness, etc). V-4s™ showed to decreases the levels of reactive oxygen species (ROS) induced by H2
O2
ozone, scavenges sulfur (RSS) and nitrogen species (RNS), and protects against lipid-peroxidation-derived reactive carbonyl species (RCS). V-4s™ combats the 4s, providing a total AntiRadical efficacy.
IPEPTIDE™, A GOOD BEAUTY SLEEP A bad sleep quality visually translates to a tired and unhealthy look with hanging eyelids, swollen eyes and dark circles. It is due to a decompensation of the circadian hormones, a chronic low inflammation and an increase of glycemia, that leads to protein glycation.
iPeptide™ modulates the exaggerated inflammatory response of the alarmin IL-33, acts as a melatonin-like, and protects skin’s proteins from glycation due to hyperglycemia because of a bad quality of sleep.
ÆONOME™, A SECRET HIDDEN 3 MILLION YEARS Æonome™ is a bacterial ferment obtained from an ancient underwater cave located in Mallorca’s Island. A unique microbial community has remained preserved & protected in this cave, unveiling Æonome™ as an agebiotic, a new approach to skin’s microbiome. Æonome™, a prebiotic metabolized by the commensal cutaneous microbiota that enhances the production and release of antioxidant metabolites and protects the skin cells from oxidative stress and signs of aging. Æonome™ increases the ability of keratinocytes to produce ageless proteins involved in skin integrity. Æonome™ efficacy reinforces the antioxidant protection of the microbiota of the skin cells’ ageless force, improving rugosity, wrinkles and hydration.
For more information visit our webpage at
www.lipotrue.com LipoTrue S.L
C/ Imaginació 12, Pol. Ind. Les Marines 08850 Gavà (Barcelona) Spain Tel: (+34) 935 477 609 Fax: (+34) 931 932 060 Email:
info@lipotrue.com
86 | LITTLE BOOK OF SKIN CARE
LipoTrue Inc. 317 George Street, Suite 320 New Brunswick, NJ 08901, USA Tel: +1(732) 839-2761 Email:
info@lipotrue.com
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