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Biotechnology & Immunology


Expanded Range of Nucleic Acid Extraction Kits for Pathogens Detection


AMSBIO announces the addition of several new products to its growing range of magnetic bead based nucleic acid extraction kits for pathogen detection. The MagSi-NA Pathogens MSP (Multiple Sample Pooling) kit sets a new benchmark for automated isolation of nucleic acids (RNA and DNA) from respiratory samples.


Traditionally one of the main disadvantages in sample pooling has been the risk of false negative results due to dilution caused by classical sample pooling methods. The MagSi-NA Pathogens MSP kit overcomes this issue by using a non-dilutive technique to sequentially capture all viral RNA present in any of up to six samples, all in a single magnetic bead pellet. Rapid and complete recovery from each sequential sample is ensured by our unique very-high-strength magnetic bead technology. The result is a nearly 6-fold increase in sample throughput and savings of up to 80% on extraction and PCR reagent costs. This is achieved without any reduction in sensitivity or increase in false negative rates.


AMSBIO’s new rQ MagSi-NA Pathogens kit provides an elegant solution for the automated isolation of nucleic acids (RNA and DNA) from a wide range of samples using magnetic particle processors. The automation-ready rQ MagSi-NA Pathogens kit, consisting of conveniently pre-filled deep- well plates, will also help labs increase throughput and allow for the preparation of up to 96 samples in less than 20 min. The pre-filled plates can be used directly in PurePrep 96, 32, 16 or KingFisher automated, nucleic acid purification systems for the extraction of pathogenic DNA and RNA to reduce hands-on time and minimises errors to achieve consistent and reproducible results.


In addition, AMSBIO has introduced a CE-IVD marked version of the existing popular Mag-Si NA pathogens kit. The new MagSi-DX Pathogens kit has been specifically validated for SARS-CoV-2 diagnostic workflow and is ideal for labs requiring CE-IVD products for use in human diagnostics. CE-IVD marked versions of MagSi-NA Pathogens MSP and rQ MagSi-NA Pathogens are scheduled for release in the coming months.


All these new kits are based on AMSBIO’s market-leading MagSi-Na Pathogens kit which uses strong magnetic beads to allow fast magnetic separation even from viscous human respiratory swabs and saliva samples to achieve consistently high yields of viral RNA, ideal for use in SARS-CoV-2 diagnostics.


More information online: ilmt.co/PL/PpGm 57317pr@reply-direct.com


Shaker Designed for CO2 Incubators


Celshak is a small, stainless steel shaker specially designed for use in CO2 incubators. The stainless steel housing with a separate controller, makes it perfect for shaking cell cultures.


Wiggens presents three models of shaker for CO2 incubators with highest quality design utilising non-belt magnetic drive technology, which allows for high performance of water resistance. The gentle drive unit features exceptionally smooth start-up and braking behaviour, and has improved oxygen


transfer and homogeneous availability of the nutrients in the culture medium. This ensures significantly better culture growth than in static cell cultures. With ultra-low power consumption, it prevents any additional heating inside the incubator.


The entire housing of shaker is made of stainless steel (SUS304), meeting the demand of GMP’s cleaning requirements and its corrosion resistant feature is ideal for using in CO2 incubators. It is easy to remove any unwanted liquids and can be cleaned with chemicals.


The thin wire cable connection between the shaker and the control box can pass through the sealing part of the inner glass door, if no access port is available within your incubator.


More information online: ilmt.co/PL/L5K5 57407pr@reply-direct.com


Deep Well Plates for High Integrity Biobanking Specimen Storage


Developed for automated applications, Porvair Sciences 96-well polypropylene microplates provide the perfect vessel for Biobanks and Biorepositories looking to store and maintain the integrity of their valuable specimens over prolonged periods of time.


Biobanking is the process by which samples of body fluids or tissue are collected for research use to improve our understanding of health and disease. However, keeping these biological specimens in long-term sample storage conditions comes with a key challenge of how to maintain their sample integrity. To combat this, biobanks and biorepositories are constantly seeking new storage methodologies and solutions that will guarantee better sample quality.


Porvair Sciences designs and manufactures 96-well round deep well plates for biobanks and biorepositories with a 2 ml liquid capacity/well in an automation compatible ANSI/SLAS footprint. Measuring just 45 mm in height, this innovative 2 ml 96-well deep well plate design incorporates features that prevent ‘locking’ when stacked and enable easy heat sealing.


Manufactured under class 100,000 conditions from ultra-pure grade polypropylene, Porvair Sciences extensive range of 24-, 48- and 96-well deep well plates are certified as RNase / DNase free and contain no measurable contaminants that could otherwise leach out and affect biological specimens.


For long term storage at -80ºC, Porvair deep well plates can be heat sealed with a wide choice foils and seals, including DMSO-safe seals, using a Ultraseal range thermal sealer to provide high integrity biological stored specimens.


More information online: ilmt.co/PL/4ppx 57468pr@reply-direct.com


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