37
Automated Solutions for Molecular Pharmacology
Image Analysis Reference Standards in Single-Shot Format
Whitehouse Scientific is now offering its image analysis particle sizing reference standards in convenient and easy-to-use, single-shot formats. Packaged in weights suitable for today’s image analysers, these multi-modal standards have shown excellent reproducibility in a recent round-robin exercise involving leading laboratories working with a variety of different image analysis systems.
Sub-sampling of reference standards by users is not recommended because of the possibility of introducing errors and thus deviations from the certified size values. To avoid any need for this, the new set of 10 standards are packaged in weights from 5 to 20 gram. This makes them highly suitable for even the latest generation of image analysis systems, which require only relatively small amounts of sample.
External testing has produced results unsurpassed in any other similar particle sizing round robin. In particular, when the test data from manufacturers of image analysis systems were collated, the eight peak positions in a multimodal standard from 500 - 2000 microns could be superimposed, showing the very close agreement between instruments for these standards.
Circle no. 137
The Leibniz-Institut für Molekulare Pharmakologie in Berlin, Germany, is using Tecan’s Freedom EVO®
workstations for
systematic high throughput screening of bioactive small molecule libraries, looking for potential research tools and targets for drug development. Dr Jens Peter von Kries, Head of the Institute’s Screening Unit, explained: “The Screening Unit has a small team of staff performing library screens of around 20,000 compounds a day, and this high throughput is partly thanks to the flexibility of our Freedom EVO workstations. Many of our projects use either high content screening with automated microscopes or genome-wide RNA interference (RNAi) studies, and we have a Freedom EVO system configured for each of these methods, as well as a platform equipped with a REMP Small Size Store™ for management of the ChemBioNet screening library.”
“Each workstation has been collaboratively designed with the Tecan Integration Group (TIG) to create a robust system that is capable of high throughput analysis, giving consistent results even with long term use. The approval procedure is central to this process, with both factory and site acceptance tests to guarantee that the platform exactly matches our needs. Tecan is very willing to support us with development of the platforms as new technologies become available, and we enjoy a very good working relationship with the company’s automation engineers, receiving immediate expert support for all our projects. Tecan has an exceptional culture of customer service, and our work here at the FMP undoubtedly benefits from this close partnership.”
Circle no. 138 Ramping up Melting Point Versatility
Stuart’s launch of the SMP20 digital melting point apparatus sets a new benchmark by offering 0.1ºC temperature resolution and an adjustable ramp rate in a cost-effective instrument.
Building on the success of the SMP10 with its high accuracy and easy operation, the SMP20 incorporates features designed to provide increased versatility. A four-digit LED display resolves temperature to 0.1 of a degree and to facilitate temperature recording, a hold button has been added. This enables the user to freeze the display at the melting point while the block temperature continues to rise. The SMP20 also provides the ability to program the ramp rate anywhere within the range 1ºC to 10ºC per minute.
For maximum ease of use the SMP20’s simple-to-follow instructions are printed directly on the instrument in most European languages. The unit heats up quickly and remains at the selected plateau temperature until the user is ready to start the test. Two samples can be tested simultaneously and these are viewed via a magnifying lens aided by built-in illumination. Extendible back feet allow operation at the optimum viewing angle and the unit’s design gives full access to the block for easier cleaning.
Jackie Taylor, Stuart Product Manager, commented: “With 0.1ºC resolution, a hold button and an adjustable ramp rate, the SMP20 represents excellent value. This new instrument makes an ideal choice for chemists in both academia and industry who require these particular features but not the advanced capabilities of a much more expensive instrument.”
The SMP20 is supplied complete with a pack of 100 melting point tubes and a calibration certificate showing the individual serial number for traceability.
Circle no. 139
Circle no. 140
INTERNATIONAL LABMATE - AUGUST/SEPTEMBER 2010 - LABORATORY PRODUCTS
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68
