The CoolRack’s cavities maintain a dry environment for the sample tube while quickly removing any heat resulting from environmental influx, effectively acting as a miniature refrigerator for each sample. The dry environment greatly reduces the opportunity for tube contents contamination.
Most importantly, however, the introduction of a simple and inexpensive technology such as the CoolRack method will result in an instant standardization of all temperature procedures for sample preparation, storage and transportation. Through the introduction of precision engineered, quality-controlled thermo-conductive CoolRacks, samples will be cooled, frozen or thawed in a highly reproducible manner. Sample temperature profiles will be identical and independent of user, time, site or location (Figure 3).
With the recognition that ice generated by conventional methods typically harbors biological contaminants, ice itself is often prohibited in critical environments such as sterile hoods, cleanrooms, GMP facilities, surgeries, and clinical settings.
When paired with an ice-free cold source and insulation, such as provided by a CoolBox, the CoolRack offers a large sample capacity, portable temperature management solution for the modern, contamination- free laboratory (Figure 4).
Figure 3. It’s All About the Curves: Highly reproducible cooling, freezing, thawing through the use of precision engineered, novel alloy sample racks. (Method: The liquid content temperature of a 1.5ml microfuge tube containing 1ml of water was monitored by insertion of a thermocouple probe. The tube was transferred from a CoolRack in 37°C waterbath to a tube profile fitting CoolRack pre- equilibrated to -78°C on dry ice, then replaced into the 37°C CoolRack. The plot of 5 consecutive cycles demonstrates identical thermal profiles).
Figure 4. Ice-free cooling/freezing solutions. Uniform, all day, ‘re-chargeable’ temperature management solution by combining thermo-conductive alloy sample racks with rechargeable cooling/freezing cartridge systems.
In summary, a closer examination and study of the decades-old ‘ice bucket’ method reveals that there are numerous limitations and pitfalls, all of which can be eliminated by the simple inclusion of highly thermo-conductive tube, plate or sample holders into sample collection, processing and handling. Quality controlled, precision-engineered novel alloy sample holders guarantee that each biomedical sample is cooled, (snap)- frozen or thawed the same way independent of time, operator or location.
ADVERTORIAL New for 2010…
We can now offer a bespoke range of cabinets for you to choose the size, volume, layout, specification and material finish.
Circle no. 161 Cooled Incubators Series 3
The LMS Series Three Cooled Incubator is a reliable and accurate temperature controlled cabinet (-10°C to +50°C) which has proved its worth over many years in laboratories both in the U.K. and overseas.
The design of the purpose built incubator facilities the addition of optional extras to provide greater flexibility for individual use, making it suitable for a wide range of applications including:-
• The study of growth patterns of plants and insects • B.O.D. Tests
• Seed germination & vernalisation • Tissue culture • Enzyme testing • Serum studies • Immunology • Fruit fly culture • Sample storage • Product shelf life tests
Circle no. 162 -10˚C to +50˚C accurate temperature controlled incubation Est. 1965 UKAS since 1994, ISO 2001..2008 since 1993
Series 1A Cooled Incubators
The LMS Series ‘1A’ Cooled Incubator is a reliable and accurate Temperature controlled cabinet (-10°C to +50°C) designed for optimum performance and reliability. The design of the purpose built incubator facilitates the addition of optional extras to provide greater flexibility for individual use, making it suitable for a wide range of applications.
Circle no. 163
Specialists in a bespoke and standard range of temperature controlled incubation cabinets
Circle no. 164
Laboratory Products Focus
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