45
Single System Provides Pure and Ultrapure Water Conveniently and Economically
Millipore Corporation has introduced the Milli-Q Direct system, the latest addition to the company’s range of Milli-Q lab water purification systems. The new system was designed to respond to the scientific community’s need for an economical, single-source solution producing pure and ultrapure water from tap. The Milli-Q Direct system provides optimum water production, with water quality that exceeds the requirements of the most demanding norms. Milli-Q Direct users are assured of having convenient and versatile water delivery: water can be dispensed either manually or automatically, at low or high flow rate. Additionally, a range of Application Pak final filters makes it possible to adapt the Milli-Q Direct system to the user’s specific application(s) by adding a BioPak®
, VOC-Pak™, EDS-Pak® , LC-Pak™ or Millipak® polisher.
The system’s low footprint will also help lab managers save on space - the Milli-Q Direct can be bench- or wall- installed to ensure the best fit with their existing laboratory configurations. Simplified procedures make maintenance for the system minimal, and an RFID tag ensures quick and easy traceability for consumables.
Circle no. 138
Circle no. 139
ANALYTICA NEWS
How To Concentrate Or Dry Samples
For laboratories tasked with concentrating or drying samples in wide ranging sample formats, Genevac presents a new online movie that demonstrates the ease of use and excellent consistent results achievable using its EZ-2 Personal Solvent Evaporator.
Using advanced evaporation science, the EZ-2 Personal Solvent Evaporator has been designed specifically for productive, sample-safe solvent removal, be that concentration of samples, or complete drying. Genevac’s long experience in vacuum engineering has resulted in the creation of a compact sample evaporator combining great performance, ease of use and compatibility with all commonly used solvents and acids.
Easily viewable via the Internet, the new movie provides an informative introduction to the science behind solvent evaporation technology. Following this the viewer is shown how the EZ-2 works.
To enable all users to achieve excellent results every time, the compact EZ-2 has been made easier to use than a conventional rotary evaporator. Capability to input up to 10 stored methods allows users to benefit from Genevac’s wealth of experience in developing optimised protocols for a wealth of applications. In addition to accommodating a wide range of sample formats it can operate entirely unattended. Simply set the temperature, select the solvent type, and press Start. The EZ-2 is fitted with an enhanced version of Genevac’s revolutionary SpeedTrap. This highly chemically resistant cold trap is designed to condense solvents, in order to protect the environment, and help to speed evaporation.
Incorporating state-of-the-art evaporation technology the EZ-2 is able to remove solvents in typically half the time of traditional evaporator designs. Requiring no peripherals for operation the compact EZ-2 fits neatly onto a laboratory bench or into a fume hood. All key components on the robust and reliable system are user serviceable ensuring low cost of ownership.
Circle no. 140
Technique for Multi-Colour Bacterial Counting
UVP, LLC defines a technique to count multiple colour bacteria colonies with the ColonyDoc-It Imaging Station. The station captures brilliant colour colony images; the software then differentiates between multiple colours when counting the colonies. The ColonyDoc-It can differentiate between b-glucuronidase positive (blue) bacteria and negative (yellow) bacteria. The results generated shows detailed counts of each colour and percentage of the population determined to be positive in b -glucuronidase.
Janelle Batman, UVP Product Manager stated: “The ColonyDoc-It’s high resolution colour camera and advanced software algorithms provide researchers with the means to finely differentiate among the myriad colours expressed by colonies.“
The ColonyDoc-It Station’s innovative design enables users to automatically count colonies quickly and accurately.
The station features: integrated high resolution digital colour camera for brilliant colour colony images; several light sources for illuminating a wide range of stained media; use of pour, spread and spiral plates and filters with sizes from 33 to 150mm; capture colony sizes as small as 0.08mm; count colonies automatically and generate detailed statistics; doors create a darkroom environment; GFP fluorescence with epi blue light and optional GFP filter; and time lapse image capture and counting.
In addition to counting multicolour bacteria colonies, the ColonyDoc-It Station can be used in applications such as microbiology, quality control, environmental and pharmaceutical.
Circle no. 141
Throwing New Light on Kidney Function
M200 microplate reader from Tecan to help investigate regulation of membrane transport in the kidneys. The group is particularly interested in the regulation of organic cation transport across the cell membrane, as Dr Giuliano Ciarimboli, deputy head of the Experimental Nephrology group, explained: “Organic cations cannot permeate the cell membrane, and are taken up by cells through membrane proteins known as organic cation transporters (OCTs). However, these proteins can also transport many drugs – such as the chemotherapy drug cisplatin – into the kidneys, with nephrotoxic consequences.”
The Experimental Nephrology laboratory at University Hospital Münster, Germany, is using an Infinite®
According to Dr Ciarimboli, the group has been investigating transport of organic cations since 1994: “Our work was earlier based on a complex microscopy technique using the fluorescent dye ASP+, however, this method was time-consuming and expensive, and we began looking for an alternative strategy to investigate delocalised cation transport. Using the Tecan Infinite M200 reader allows us to work in 96-well microplate format, significantly increasing throughput and minimising reagent usage. The Infinite’s dual injector option allows ASP+ to be injected together with another OCT substrate, for rapid determination of IC50 values. The microplate technique shows very good correlation with our microscopy-based method, achieving near identical inhibition curves. Moreover, this technique is also suitable to investigate acute regulation of the transporters.”
He concluded: “Tecan has been very supportive of our work here, and we always receive expert assistance when we are developing new techniques.”
Circle no. 142
INTERNATIONAL LABMATE - APRIL/MAY 2010 - LABORATORY PRODUCTS
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