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www.us-tech.com
February, 2018 Cogiscan and MIRTEC... Continued from page 1
technology is a staple of the electron- ics industry. We want to partner with the best company to provide the best value to our customers.” Co-NECT is built on the stan-
Neu Dynamics Corp is an ISO 9001:2008 certified Tool, Mold and Die man- ufacturer
specializing in tooling and equipment used in building
Semiconductors, Electronics, components and a wide variety of the devices used in automotive, telecommunications, solar and medical applications. We further offer small to medium volume contract molding services for
microelectronic packages such as BGA, QFN, MLP, optical components etc. We also have capability to provide insert molding services for items such as connectors.
CONTRACT MOLDING OVERMOLDING TOOLING
Phone 215-355-2460 CUSTOM MACHINING
MOLD DESIGN AND FABRICATION
WWW.NEUDYNAMICS.COM SALES@NEUDYNAMICS.COM
Fax 215-355-7365 Specialized Coating Services Continued from page 1
facility include AS9100D, ISO 9001:2015, ITAR, and ANSI/ESD S20.20 mid-2018, with NADCAP planned for late 2018. “With these certifications, our customers know that their boards will be handled in compliance with the latest practices and procedures,” says Atkins. The investment in the new U.S.
NDC International offers specialized equipment built for today's high-tech semiconductor assembly processes.
HANMI SEMICONDUCTOR
MPP MANUAL WIRE BONDERS
K&S CAPILLARIES K&S DICING BLADES
MASTER MACHINERY CUSTOM AUTOMATION RGT WAFER FRAMES
RGT MANUAL WAFER MOUNTER
WWW.NDC-INT.COM
facility underscores the company’s commitment to reshoring manufactur- ing jobs and growing the business. Specialized Coating Services has re- designed its website to focus on the in- formation that potential buyers need to make purchasing decisions. The company also focused on developing a strategic presence on
ThomasNet.com, a popular product sourcing and suppli- er discovery website. As a result, the company has
grown from a local service provider to a global specialist, attracting worldwide accounts and bringing manufacturing jobs back to the U.S. One specific customer that made a connection through
ThomasNet.com
manufactures between 3,000 and 5,000 parts per month and ships them to Specialized Coating Servic- es before final assembly.
dard Cogiscan TTC platform that was created more than 15 years ago. It adapts to each individual cus- tomer’s requirements, regardless of the mix of machines and software al- ready in place. Mitch Decaire, global account manager for equipment part- ners at Cogiscan, said, “We are very
excited to announce this new part- nership. We look forward to helping MIRTEC and its customers gain a competitive edge by achieving the connected factory.” Contact: Cogiscan, Inc., 28-B
boulevard de l’Aeroport, Bromont, Quebec, Canada J2L 2N8 % 450- 534-2644 E-mail:
info@cogiscan.com Web:
www.cogiscan.com and MIRTEC Corp., 3 Morse Road, Ox- ford, CT 06478 % 203-881-5559 fax: 203-881-3322 E-mail:
bdamico@mindspring.com Web:
www.mirtec.com r
Specialized Coating Services' cofounders Kim Atkins (left) and Rick Ramirez (right).
Contact: Specialized Coating
Services, 42680 Christy Street, Fremont, CA 94538 % 510-226-8742 E-mail:
rick@speccoat.com Web:
www.speccoat.com r
Organ-on-a-Chip... Continued from page 6
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The bottom contains air while the top contains a flowing fluid similar in mechanical properties to blood. In- side the fluid-filled chamber on top of the membrane, the researchers grow endothelial cells — the cells that line the inside of blood vessels. The re- searchers pump air into the bottom chamber, so the membrane stretches like a balloon and forms a bubble that blocks the fluid flow. This process simulates the narrowing of a vessel. The fluid-filled chamber con-
stricts, causing the fluid to flow faster in some regions and slower in others. When the researchers grew the cells under continuous but slow fluid flow, endothelial cells were able to grow and express a protein called ICAM-1. This protein is asso- ciated with inflammation and is im- portant in the development of ather- osclerosis. The researchers found that
when they replaced the cell culture media with human blood, more im- mune cells called monocytes bound to the endothelial cells in low-flow re- gions. Monocytes are mainly respon- sible for the accumulation of lipids, which eventually develop into the plaque that causes atherosclerosis. These results on a chip are con-
sistent with the widely-accepted pic- ture of the disease: Disturbed blood
flow in constricted vessels promotes vascular inflammation, which en- courages the recruitment of mono- cytes to help create plaques. “The new model can more accurately sim- ulate atherosclerosis because the re- searcher can precisely tune constric- tion by controlling the air pressure,” Hou says. This device could poten- tially help researchers better under- stand atherosclerosis and develop new treatments. “The device has a lot of promise
in terms of diagnostics,” Hou says. As a proof-of-concept experiment, the re- searchers pumped blood spiked with TNF-alpha, a protein that is a sign of inflammation, into their device. The inflamed blood caused more immune cells to bind to the endothelial cells than normal. Measuring the number of bound immune cells can reveal the level of inflammation in the blood, an indicator of early atherosclerosis. In contrast to other tests that only count the number of immune cells circulating in blood, this technique could more accurately assess early immune responses in patients. Web:
www.aip.org r
The full article, “A Tunable Mi-
crofluidic 3D Stenosis Model to Study Leukocyte-Endothelial Interactions in Athersclerosis,” can be found at:
www.aip.scitation.org/doi/full/10.1 063/1.4993762
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