International Chemistry Prize for Strathclyde Researcher
University of Strathclyde student Joshua Barham, was named a winner of the prestigious Reaxys PhD Prize, an annual international award for outstanding young chemistry researchers. He received his prize and a cheque for $2000 following his presentation at a symposium held by Reaxys in Shanghai.
A graduate of a pioneering collaborative PhD programme offered by Strathclyde and pharmaceutical company GlaxoSmithKline (GSK), Joshua said: “I’m thrilled to win. It’s a testament to all the hard work I poured in to my PhD and to the efforts of those who supported me along the way. I’m deeply grateful to people involved in the collaborative PhD programme; it feels fantastic to be able to promote the international visibility and reputation of the PhD programme and of Strathclyde, through winning this prize.”
Joshua’s research, based on previously-published work, explored the selective abstraction of hydrogen atoms from complex molecules, for potential use in medicine – with unexpected results. “We realised these chemical reagents could be applied in a different way and deployed for the industrially applicable transformation we were seeking.
“Serendipitously, we found that, in our case, the chemistry proceeded totally differently to the way we originally intended and were amazed at the remarkable opportunities that it afforded for selectively targeting specific molecular sites. Medicinal chemists can use our method to target and functionalise specific sites of complex molecules to test how the molecular structure at those sites influences pharmacological activity.
“This is critically important in the field of synthetic opiate medicines - used to treat opiate addictions or overdose - where small changes in molecular structure can completely reverse pharmacological activity. For example, a very small change in molecular structure can transform an analgesic molecule 10 times more potent than morphine into a molecule used to treat opiate overdose.”
He is currently based in Japan moving between the National Institute of Advanced Industrial Science and Technology (AIST) in Tokyo and the University of Shizuoka, working on a collaborative project developing and evaluating new ‘flow chemistry’ reactors that use microwave heating technology.
44414pr@reply-direct.com Joshua Barham with his Reaxys PhD Prize
4 Days of Exciting Science at PREP 2018
PREP 2018: 31st International Symposium and Exhibit on Preparative and Process Chromatograph, 8-11 July, Hyatt Regency, Baltimore Inner Harbor, MD, USA,
Join us for four days of exciting science, technology and education at PREP2018, the longest running, widely recognised international scientific conference and exposition driving the field of Preparative and Process Chromatography, organised by expert scientists and engineers for the separation science practitioner. PREP2018 offers a dynamic and innovative program where world-renowned speakers will address in-depth the latest scientific and technological advances, critical and emerging applications and processes, and challenges and solutions in all aspects of Preparative and Process Chromatography.
The focus of this conference is the development, design, optimisation and operation of chromatographic processes and technology for a broad range of applications. The program will be packed with papers on biochromatography, downstream processing, QbD, monoclonal antibodies, plasmids, enzymes, vaccines, viral vectors for gene delivery, VLPs, and other biopharmaceuticals, chiral molecules, SFC, fine chemicals, peptides, proteins, oligonucleotides, APIs, natural products, batch, multi-column and continuous SMB processes, column technology and equipment, monoliths, new and improved stationary phases, membrane chromatography, regulatory aspects and more!
EMERGING APPLICATIONS AND PROCESSES
The Symposium will provide opportunities to present, discuss and learn about the latest scientific and technological advances in preparative chromatography; to gain an in- depth exposure to the most recent chromatography products and technologies on the market; to obtain training and education to develop and optimise processes and minimise costs in the production of fine chemicals, chiral molecules,
natural products, active pharmaceutical ingredients, peptides, oligonucleotides, proteins, monoclonal antibodies, plasmids, vaccines, viral vectors for gene delivery, VLPs and other biopharmaceuticals; and to access a vast network of separation scientists and engineers working on the most relevant process aspects including continuous and integrated manufacturing, process control and mechanistic modelling.
PRELIMINARY LIST OF KEYNOTE SESSIONS
In addition to general oral and poster sessions, PREP2018 will feature keynote sessions addressing critical and emerging areas in preparative chromatography such as:
• Industrial Case Studies in Protein Chromatography
• Continuous Chromatography for APIs, Fine Chemicals, and Natural Products
• Continuous Manufacturing and Downstream Processing for Biopharmaceuticals
• Preparative Chromatography in Drug Discovery, Development, and Manufacture
• Process Scale Purification of Peptides • Preparative Supercritical Fluid Chromatography
• Big Data and Hybrid Modeling in Preparative/ Process Chromatography
TRAINING WORKSHOPS AND TUTORIALS
The Sunday Training Workshops provide in-depth coverage of both fundamentals and real-world applications of preparative chromatography for biomolecules and for small and intermediate molecules. The Monday and Tuesday morning Tutorials address more specialised topics. For further details, visit
http://www.prepsymposium.org/workshop-tutorial.html
VENDOR EXHIBITS AND WORKSHOPS The 2-1/2 day Exhibit (Sunday evening through Tuesday
Professor Giorgio Carta, PREP Symposium Chairman
afternoon) will provide access to the latest advances in chromatographic media, equipment and services with ample opportunities to meet commercial suppliers in the closely integrated lecture and poster/trade display areas within the facility. Exhibitors and sponsors will also have the opportunity to present sponsored vendor workshops that are free to Symposium participants as well as to present in a ‘rapid-fire’ oral session to highlight their latest products and technologies.
Learn more at
www.PREPsymposium.org 44768pr@reply-direct.com
Italian Scientist Wins 2017 Eppendorf & Science Prize
The Italian scientist Flavio Donato, PhD has won the 2017 Eppendorf & Science Prize for Neurobiology for his work on the driving forces that orchestrate the maturation of circuits representing space in the brain.
Flavio Donato
Dr Donato carried out his research in the laboratory of Professors May-Britt Moser and Edvard Moser at the Kavli Institute of the Norwegian University of Science and Technology in Trondheim. Flavio Donato’s work has revealed that, during development, stellate cells in the medial entorhinal cortex are the source of an activity-dependent instructive signal necessary for the maturation of those neurons that give us a sense of where we are. This finding proves the existence of autonomous, intrinsic drivers that guide the maturation of widespread regions of cortex from deep within the brain. Unravelling the unique contribution of these specific neuronal populations to the
function of neural circuits will advance our understanding of how the brain processes abstract cognitive functions.
The annual US$25,000 Eppendorf & Science Prize for Neurobiology honours scientists, like Dr Donato, for their ground-breaking research. Flavio Donato is the 16th recipient of this international prize which is awarded jointly by Eppendorf and the journal Science. Researchers who are 35 years of age or younger and have made outstanding contributions to neurobiological research based on methods of molecular and cell biology are invited to apply. The next deadline for applications is 15 June, 2018. For more information about Dr Donato and the Eppendorf and Science Prize for Neurobiology, visit
www.eppendorf.com/prize.
44320pr@reply-direct.com
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