The latest Business updates from the science industry
by Heather Hobbs Activate Science Has Been all Over Europe
Activate Science, an annual event series organised by Thermo Fisher Scientifi c and attended by laboratory personnel across Europe, reached delegates at 28 customer sites in 2017.
Emily Quinton, European Marketing Communications Manager, commented: “Activate Science has reached nearly 3,000 delegates in eight European countries during the year and provided a valuable
opportunity to network and get hands-on with all the latest products at a customer site.”
Activate Science events are aimed at all laboratory personnel, including anyone who uses or purchases products. Delegates have commented that they value being able to talk to suppliers in a relaxed atmosphere away from the laboratory. They also enjoy seminars covering topics relevant to their work as well as learning about new
techniques and developments that enable them to make the world healthier, cleaner and safer.
For more information relating to the Activate Science programme across Europe, please visit
www.eu.fi shersci.com/go/activatescience.
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New CEO to Drive Clinical Phase Development
Zelluna Immunotherapy, a biotechnology company specialising in T-cell receptor (TCR) immunotherapies targeting a broad range of solid cancers, has appointed Miguel Forte as chief executive offi cer (CEO).
“Zelluna is developing a unique immunotherapy portfolio of non-engineered tumour specifi c T-cell receptors (TCRs) isolated from long term survivors from cancer vaccine trials conducted by former Professor Gustav Gaudernack’s group at the Oslo University Hospital. This enables Zelluna to target some of the most common cancer antigens and cancer types. Its established partnerships also grant critical support including all capabilities of TCR development, one of Europe’s largest academic GMP cell therapy production facilities headed by professor Gunnar Kvalheim and access to patients and clinical trial support through a dedicated Clinical Trial Unit,” said Anders Tuv, chairman of the board, Zelluna. “Appointing a CEO with the international experience and profi le of Miguel Forte will be critical to further enhance the therapeutic, development and
Miguel Forte
commercial potential of Zelluna and push its leadership position in the international TCR and immunotherapy marketplaces.”
Miguel is tasked with driving clinical translation of the TCR pipeline, developing new international scientifi c and commercial partnerships and forging relationships with the international investor communities.
With extensive commercial experience in the regenerative medicine, cell therapy, medical and regulatory affairs industries, Miguel is also currently chief commercialisation offi cer and chair of the commercialisation committee for the International Society of Cellular Therapy, the global society of clinicians, researchers, regulatory specialists, technologists and industry partners in the cell therapy sector.
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Investment to Support Technology Roll-Out
Biomanufacturing company Univercells SA, has announced the successful closing of a €3 million ($3.56M) increase in a Series-A equity fi nancing round, led by private investors from Europe and the US.
Grant Boosts Cargo Delivery in Genomes Project
EMBL spin-out Geneva Biotech, a developer of viral and non-viral DNA delivery systems and Sphere Fluidics, providers of single cell analysis systems, have received a €1.6 million grant from the Eurostars funding programme that supports international collaborations between R&D- performing small and medium enterprises to develop innovative products, processes and services.
The grant will support a project that aims to adapt the use of Sphere Fluidics’ Cyto-Mine Single Cell Analysis System to generate an automated, benchtop device for precise docking of very large DNA cargoes in genome-edited cell lines. Cyto-Mine uses picodroplet technology and microfl uidics to encapsulate cells in a picodroplet containing growth medium; this acts as a bioreactor to compartmentalise the cell and let it grow, eventually trapping secreted molecules such as antibodies. The unique workfl ow enables selective screening of single cells to fi nd rare lead candidates.
Dr Frank Craig, CEO and Director at Sphere Fluidics said: “Sphere Fluidics is adapting the use of its Cyto-Mine system for the genome editing fi eld. The Eurostars programme will enable us to continue to expand its use in this rapidly growing market by working together with Geneva Biotech to develop a precise method of delivering large DNA cargoes in genomes.”
Dr Daniel Fitzgerald, CEO and Director at Geneva Biotech commented: “Geneva Biotech has a long term vision to create viral vector tools that enable large DNA cargo delivery and genome engineering in primary cells that have proven refractory to traditional transfection, electroporation, or transduction methods. The Eurostars collaboration with Sphere Fluidics forms a key part of our strategy to improve our position in this fi eld with signifi cant therapeutic and industrial importance.”
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The capital injection will help enable the commercial introduction of the company’s viral micro-facility, with a fi rst technology transfer anticipated for Q4 2018 within the framework of the Bill & Melinda Gates Foundation-supported program; it will also benefi t the company’s recombinant platform development, both of which are aimed at providing a suffi cient supply of high-quality biologics at an affordable price.
“We are very proud of this funding round and thankful for this wealth of support,” commented Hugues Bultot, co-founder and CEO of Univercells. “This successful capital increase is a real recognition of the work achieved so far, the innovative technology being developed and the clear expectations and roadmap set. It is highly encouraging to have seasoned industry experts demonstrate such tremendous confi dence in Univercells, its ability to transform the industry with their willingness to contribute to our mission.”
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