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8 ANALYTICAL AND LABORATORY EQUIPMENT


Labs turn to automation for improved technology integration


The latest automation technologies are designed to improve the integration of laboratory equipment - increasing speed of analyses at the same time as reducing running costs. Sean Ottewell reports.


Les toutes dernières technologies d’automatisation sont conçues pour améliorer l’intégration des équipements de laboratoire, augmentant ainsi la vitesse des analyses tout en réduisant les coûts. Un article de Sean Ottewell.


Die neuesten Automatisierungstechniken wurden zur Verbesserung der Integration der Laborausrüstung – zur Erhöhung der Analysengeschwindigkeit und zur gleichzeitigen Senkung der laufenden Kosten – entwickelt. Sean Ottewell berichtet.


A


B Sciex, a global leader in analytical technology, has announced the


availability of new software and service offerings to simplify and accelerate the integration of its micro LC technology into regulated bioanalytical laboratories.


Te addition of a new software module supporting 21CFR Part 11 and a new IQ/OQ/PQ service to the Eksigent line of liquid chromatography solutions gives pharmaceutical companies, contract research organisations (CROs) and other high-throughput laboratories the opportunity to use a validated approach to micro LC for increasing sensitivity and speed while reducing the cost of running a laboratory.


Regulated bioanalytical labs have been looking for ways to improve productivity and efficiency for their absorption, distribution, metabolism, and excretion (ADME) and bioanalysis assays but haven’t been able to take advantage of micro LC because of the lack of tools and precedence to integrate it into an existing lab that follows good laboratory practice (GLP)


regulations. Te new 21CFR Part 11 module and the new service to qualify the LC system for GLP solve this dilemma for regulated labs by eliminating any doubt that a micro LC solution can be configured to meet required rules and regulations.


For researchers looking for improved sensitivity, efficiency and cost savings, micro LC technology such as the Eksigent ekspert microLC 200 UHPLC system delivers up to a four-fold increase in sensitivity and as much as a three-fold increase in throughput while minimising sample injection volumes. It also can reduce solvent consumption and costs by up to 95 per cent.


Among the regulated labs that are using micro LC is Alturas Analytics, a CRO that provides LC/MS-based services to the pharmaceutical and biotech industries. Scientists at Alturas are using an Eksigent micro LC solution along with AB SCIEX QTRAP technology for an integrated quantitative/qualitative approach.


“By improving the limits of detection with micro LC technology, regulated labs can improve results in


Fig. 1. SmartCapture provides automated daily capture of detailed utilisation information for all instruments in a lab, regardless of manufacturer, technique and control software.


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